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HTR2C 抗体 (Internal Region)

HTR2C 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257909
发货至: 中国
  • 抗原 See all HTR2C 抗体
    HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
    抗原表位
    • 15
    • 9
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 73
    • 43
    • 42
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 69
    • 3
    • 1
    克隆类型
    • 62
    • 11
    多克隆
    标记
    • 35
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HTR2C antibody is un-conjugated
    应用范围
    • 59
    • 31
    • 14
    • 13
    • 13
    • 12
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    5HT2C Receptor Antibody detects endogenous levels of total 5HT2C Receptor.
    预测反应
    Pig,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human 5HT2C Receptor, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product HTR2C Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
    别名
    HTR2C (HTR2C 产品)
    别名
    5-HT2C antibody, 5-HTR2C antibody, HTR1C antibody, 5-HT2cR antibody, 5HT1c antibody, Htr1c antibody, SR1 antibody, 5HT-1C antibody, 5HT2C antibody, 5-HT-2C antibody, 5-ht2cr antibody, si:dkey-24g18.2 antibody, 5ht2c antibody, 5HTR2C antibody, 5-hydroxytryptamine receptor 2C antibody, 5-hydroxytryptamine (serotonin) receptor 2C antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 antibody, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antibody, HTR2C antibody, Htr2c antibody, htr2c.S antibody, htr2cl1 antibody, LOC407134 antibody
    背景

    Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.

    Gene: HTR2C

    分子量
    55 kDa
    基因ID
    3358
    UniProt
    P28335
    途径
    Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
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