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TEAD1 抗体 (Internal Region)

TEAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257778
发货至: 中国
  • 抗原 See all TEAD1 抗体
    TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
    抗原表位
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 27
    • 11
    • 10
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 26
    • 3
    克隆类型
    • 23
    • 6
    多克隆
    标记
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TEAD1 antibody is un-conjugated
    应用范围
    • 22
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    TEAD1 Antibody detects endogenous levels of total TEAD1.
    预测反应
    Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TEAD1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product TEAD1 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl,sodium azide and glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
    别名
    TEAD1 (TEAD1 产品)
    别名
    tead1 antibody, zgc:63696 antibody, TEAD1 antibody, xtead1 antibody, 2610024B07Rik antibody, B230114H05Rik antibody, Gtrgeo5 antibody, TEAD-1 antibody, TEF-1 antibody, Tcf13 antibody, mTEF-1 antibody, AA antibody, NTEF-1 antibody, REF1 antibody, TCF-13 antibody, TCF13 antibody, XNTEF-1 antibody, xlNTEF-1 antibody, TEA domain family member 1a antibody, TEA domain transcription factor 1 antibody, TEA domain family member 1 (SV40 transcriptional enhancer factor) antibody, TEA domain family member 1 antibody, TEA domain family member 1 (SV40 transcriptional enhancer factor) S homeolog antibody, TEA domain family member 1b antibody, tead1a antibody, TEAD1 antibody, tead1 antibody, Tead1 antibody, tead1.S antibody, tead1b antibody
    背景

    Description: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.

    Gene: TEAD1

    分子量
    48 kDa
    基因ID
    7003
    UniProt
    P28347
    途径
    Regulation of Lipid Metabolism by PPARalpha
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