KCNA5 抗体 (Internal Region)
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- 抗原 See all KCNA5 抗体
- KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))
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抗原表位
- Internal Region
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNA5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- KCNA5 Antibody detects endogenous levels of total KCNA5.
- 预测反应
- Pig,Bovine,Horse,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human KCNA5, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) (AA 72-121) antibody
KCNA5 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) (1st Extracellular Loop), (AA 268-279) antibodyKCNA5 适用: 人, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) antibodyKCNA5 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) (AA 513-602), (C-Term), (Intracellular) antibody (Atto 550)KCNA5 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal Atto 550
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- KCNA5 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))
- 别名
- KCNA5 (KCNA5 产品)
- 别名
- KCNA5 antibody, kcna5 antibody, ATFB7 antibody, HCK1 antibody, HK2 antibody, HPCN1 antibody, KV1.5 antibody, PCN1 antibody, Kv1.5 antibody, Kv1 antibody, potassium voltage-gated channel subfamily A member 5 antibody, potassium channel, voltage gated shaker related subfamily A, member 5 antibody, potassium voltage-gated channel, shaker-related subfamily, member 5 antibody, KCNA5 antibody, kcna5 antibody, Kcna5 antibody
- 背景
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Description: Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well, channel properties depend on the type of alpha subunits that are part of the channel (PubMed:12130714). Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation (PubMed:12130714). Homotetrameric channels display rapid activation and slow inactivation (PubMed:8505626, PubMed:12130714). May play a role in regulating the secretion of insulin in normal pancreatic islets. Isoform 2 exhibits a voltage-dependent recovery from inactivation and an excessive cumulative inactivation (PubMed:11524461).
Gene: KCNA5
- 分子量
- 68 kDa
- 基因ID
- 3741
- UniProt
- P22460
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