电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

RPL11 抗体 (C-Term)

RPL11 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257632
发货至: 中国
  • 抗原 See all RPL11 抗体
    RPL11 (Ribosomal Protein L11 (RPL11))
    抗原表位
    • 15
    • 12
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 44
    • 31
    • 29
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 55
    • 4
    克隆类型
    • 56
    • 3
    多克隆
    标记
    • 25
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RPL11 antibody is un-conjugated
    应用范围
    • 46
    • 26
    • 13
    • 13
    • 10
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    RPL11 Antibody detects endogenous levels of total RPL11.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RPL11, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product RPL11 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    RPL11 (Ribosomal Protein L11 (RPL11))
    别名
    RPL11 (RPL11 产品)
    别名
    DBA7 antibody, GIG34 antibody, L11 antibody, 2010203J19Rik antibody, BcDNA:LD17235 antibody, CG7726 antibody, DL11 antibody, Dmel\\CG7726 antibody, EST A antibody, RPL11 antibody, Rp L11 antibody, l(2)k16914 antibody, rpl11 antibody, zgc:86748 antibody, ribosomal protein L11 antibody, 50S ribosomal protein L11 antibody, Ribosomal protein L11 antibody, ribosomal protein L11 L homeolog antibody, cap binding complex dependent translation initiation factor antibody, RPL11 antibody, Rpl11 antibody, rpl11 antibody, RpL11 antibody, rpl11.L antibody, CTIF antibody
    背景

    Description: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs (PubMed:19061985, PubMed:12962325, PubMed:24120868). It also couples ribosome biogenesis to p53/TP53 activation. As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53 (PubMed:24120868). Promotes nucleolar location of PML (By similarity).

    Gene: RPL11

    分子量
    20 kDa
    基因ID
    6135
    UniProt
    P62913
You are here:
客服