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WTAP 抗体 (C-Term)

WTAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257553
发货至: 中国
  • 抗原 See all WTAP 抗体
    WTAP (Wilms Tumor 1 Associated Protein (WTAP))
    抗原表位
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 50
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 43
    • 7
    克隆类型
    • 42
    • 8
    多克隆
    标记
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WTAP antibody is un-conjugated
    应用范围
    • 36
    • 27
    • 14
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    WTAP Antibody detects endogenous levels of total WTAP.
    预测反应
    Horse,Sheep,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human WTAP, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product WTAP Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    WTAP (Wilms Tumor 1 Associated Protein (WTAP))
    别名
    WTAP (WTAP 产品)
    别名
    MGC75954 antibody, WTAP antibody, RGD1563824 antibody, wu:fi29a09 antibody, zgc:66202 antibody, 2810408K05Rik antibody, 9430038B09Rik antibody, WT1 associated protein antibody, Wilms tumor 1 associated protein antibody, wilms tumor 1 associated protein antibody, WT1 associated protein L homeolog antibody, Wilms tumour 1-associating protein antibody, wtap antibody, WTAP antibody, CpipJ_CPIJ006489 antibody, Wtap antibody, wtap.L antibody
    背景

    Description: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).

    Gene: WTAP

    分子量
    44 kDa
    基因ID
    9589
    UniProt
    Q15007
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