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PFKL 抗体 (C-Term)

Name: PFKL 抗体 (C-Term)
SKU: ABIN6257021
Availability: OutOfStock

PFKL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts from A549 cells using K6PL antibody.

IF/ICC

2 images

产品编号 ABIN6257021

发货至: 中国

Datasheet as PDF

抗原 See all PFKL 抗体

PFKL (Phosphofructokinase, Liver (PFKL))
抗原表位
8

6

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
43

24

16

3

3

2

2

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
40

5
兔
Compatible Secondaries
克隆类型
41

4
多克隆
标记
29

3

3

2

1

1

1

1

1

1

1

1
This PFKL antibody is un-conjugated
应用范围
33

17

17

6

5

3

3

3

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

K6PL Antibody detects endogenous levels of total K6PL.

预测反应

Pig,Bovine,Horse,Sheep,Dog,Chicken

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human K6PL, corresponding to a region within C-terminal amino acids.

亚型

IgG

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anti-Phosphofructokinase, Liver (PFKL) (Center) antibody
PFKL 适用: 人, 小鼠 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Phosphofructokinase, Liver (PFKL) (AA 229-479) antibody
PFKL 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Phosphofructokinase, Liver (PFKL) (AA 700-780) antibody
PFKL 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Phosphofructokinase, Liver (PFKL) (Middle Region) antibody
PFKL 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Phosphofructokinase, Liver (PFKL) (C-Term) antibody
PFKL 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Phosphofructokinase, Liver (PFKL) (AA 371-399) antibody
PFKL 适用: 人 WB 宿主: 兔 Polyclonal RB6851 unconjugated

anti-Phosphofructokinase, Liver (PFKL) (C-Term) antibody
PFKL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Phosphofructokinase, Liver (PFKL) (AA 441-540) antibody
PFKL 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A9 unconjugated

anti-Phosphofructokinase, Liver (PFKL) (AA 669-699), (C-Term) antibody
PFKL 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03903 unconjugated

anti-Phosphofructokinase, Liver (PFKL) (AA 1-827) antibody
PFKL 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

应用备注

WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

PFKL (Phosphofructokinase, Liver (PFKL))

别名

PFKL (PFKL 产品)

别名

PFK-B antibody, AA407869 antibody, phosphofructokinase, liver type antibody, phosphofructokinase, liver, B-type antibody, PFKL antibody, Pfkl antibody

背景

Description: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (By similarity).
Gene: PFKL

分子量

85 kDa

基因ID

5211

UniProt

P17858

途径

Negative Regulation of Hormone Secretion, Warburg Effect