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- 抗原 See all IL21 Receptor (IL21R) 抗体
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
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抗原表位
- AA 20-240
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL21 Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GVSMPRGWAA PLLLLLLQGG WGCPDLVCYT DYLQTVICIL EMWNLHPSTL TLTWQDQYEE LKDEATSCSL HRSAHNATHA TYTCHMDVFH FMADDIFSVN ITDQSGNYSQ ECGSFLLAES IKPAPPFNVT VTFSGQYNIS WRSDYEDPAF YMLKGKLQYE LQYRNRGDPW AVSPRRKLIS VDSRSVSLLP LEFRKDSSYE LQVRAGPMPG SSYQGTWSEW S
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human IL21R (NP_851565.4).
- 亚型
- IgG
- Top Product
- Discover our top product IL21R Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
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Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
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- 抗原
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
- 别名
- IL21R (IL21R 产品)
- 别名
- IL21R antibody, il-21ra.a antibody, CD360 antibody, NILR antibody, interleukin 21 receptor antibody, interleukin 21 receptor, tandem duplicate 1 antibody, IL21R antibody, il21r.1 antibody, Il21r antibody
- 背景
- The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.,IL21R,CD360,NILR,Immunology & Inflammation,CD markers,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL21R
- 分子量
- 59 kDa
- 基因ID
- 50615
- UniProt
- Q9HBE5
- 途径
- JAK/STAT Signaling
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