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IKKi/IKKe 抗体 (AA 495-716)

IKBKE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6213715
发货至: 中国
  • 抗原 See all IKKi/IKKe (IKBKE) 抗体
    IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
    抗原表位
    • 15
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 495-716
    适用
    • 61
    • 26
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 71
    • 6
    克隆类型
    • 63
    • 14
    多克隆
    标记
    • 34
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This IKKi/IKKe antibody is un-conjugated
    应用范围
    • 61
    • 33
    • 16
    • 16
    • 16
    • 14
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LRSRLRTLAE VLSRCSQNIT ETQESLSSLN RELVKSRDQV HEDRSIQQIQ CCLDKMNFIY KQFKKSRMRP GLGYNEEQIH KLDKVNFSHL AKRLLQVFQE ECVQKYQASL VTHGKRMRVV HETRNHLRLV GCSVAACNTE AQGVQESLSK LLEELSHQLL QDRAKGAQAS PPPIAPYPSP TRKDLLLHMQ ELCEGMKLLA SDLLDNNRII ERLNRVPAPP DV
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 495-716 of human IKKepsilon (NP_054721.1).
    亚型
    IgG
    Top Product
    Discover our top product IKBKE Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • He, Ma, Tian, Wei, Zhu, Li, Zhang, Wang, Zhang, Zhong: "ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006347, (2017) (PubMed).

    Gao, Yang, Yuan, Huang, Xu, Mao, Yuan, Bi: "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration." in: Oncogenesis, Vol. 6, Issue 9, pp. e383, (2017) (PubMed).

  • 抗原
    IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
    别名
    IKBKE (IKBKE 产品)
    别名
    zgc:100844 antibody, IKBKE antibody, MGC130907 antibody, IKK-E antibody, IKK-i antibody, IKKE antibody, IKKI antibody, AW558201 antibody, IKKepsilon antibody, Ikki antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon antibody, inhibitor of nuclear factor kappa B kinase subunit epsilon antibody, inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog antibody, inhibitor of kappaB kinase epsilon antibody, IKBKE antibody, ikbke antibody, ikbke.L antibody, Ikbke antibody
    背景
    IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30 % of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009],IKBKE,IKK-E,IKK-i,IKKE,IKKI,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Death Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,IKBKE
    分子量
    70 kDa/80 kDa
    基因ID
    9641
    UniProt
    Q14164
    途径
    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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