MVP 抗体
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- 抗原 See all MVP 抗体
- MVP (Major Vault Protein (MVP))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MVP antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 原理
- Mouse Monoclonal anti-Major Vault Protein (MVP) (1032), Purified, BSA-free
- 产品特性
- This antibody recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70 % of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 纯化方法
- Purified
- 免疫原
- Proteins precipitated from human breast cancer MCF-7 cells
- 克隆位点
- 1032
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product MVP Primary Antibody
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anti-Major Vault Protein (MVP) (AA 1-893) antibody
MVP 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2H3-1A6 unconjugated
anti-Major Vault Protein (MVP) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) (AA 2-272) antibodyMVP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) (C-Term) antibodyMVP 适用: 人 WB, FACS, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyKO Validated MVP 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) (AA 2-259) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) (AA 88-180) antibodyMVP 适用: 人, 斑马鱼 FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyMVP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Major Vault Protein (MVP) antibodyMVP 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 1014 unconjugated
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- 应用备注
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- 说明
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MCF-7/HeLa, breast tumors
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS (no BSA, no azide)
- 储存液
- Azide free
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- 抗原
- MVP (Major Vault Protein (MVP))
- Abstract
- MVP 产品
- 别名
- LRP antibody, VAULT1 antibody, 2310009M24Rik antibody, cb771 antibody, wu:fb52b05 antibody, wu:fc02g01 antibody, mvp antibody, MGC145641 antibody, Tb05.45E22.810 antibody, major vault protein antibody, major vault protein L homeolog antibody, putative major vault protein antibody, MVP antibody, Mvp antibody, mvp antibody, mvp.L antibody, Tc00.1047053510353.10 antibody, Tb927.5.4460 antibody, Tb10.70.0520 antibody, Tb10.70.5840 antibody, LMJF_05_0060 antibody
- 背景
- Lung resistance-related protein (LRP), Major Vault Protein, MVP, VAULT1
- 分子量
- 104-110 kDa
- 基因ID
- 9961, 632177
- UniProt
- Q14764
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