MALT1 抗体 (AA 701-808)
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- 抗原 See all MALT1 抗体
- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
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抗原表位
- AA 701-808
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MALT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 原理
- Mouse Monoclonal anti-MALT-1 (MT1/410), Purified, BSA-free
- 产品特性
- Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11,18)(q21,q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 纯化方法
- Purified
- 免疫原
- Human MALT1 recombinant fragment (aa701-808)
- 克隆位点
- MT1-410
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product MALT1 Primary Antibody
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anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 125-450) antibody
MALT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal MT1-410 unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (Internal Region) antibodyMALT1 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal rMT1-410 unconjugated Recombinant Antibody
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 IHC (f) 宿主: 兔 Monoclonal MT1-3159R unconjugated Recombinant Antibody
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 685-784) antibodyMALT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) antibodyMALT1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blotting 0.5-1 μg/mL, Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Jurkat, Daudi or HeLa cells. Tonsil or lymphoma.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS (no BSA, no azide)
- 储存液
- Azide free
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- 抗原
- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
- 别名
- MALT-1 (MALT1 产品)
- 别名
- malt1 antibody, MALT1 antibody, mlt antibody, mlt1 antibody, MLT antibody, MLT1 antibody, A630046N12 antibody, D430033E09Rik antibody, MALT paracaspase 2 antibody, MALT1 paracaspase antibody, MALT1 paracaspase S homeolog antibody, paracaspase 3 antibody, malt2 antibody, MALT1 antibody, malt1.S antibody, Malt1 antibody, PCASP3 antibody
- 背景
- Caspase-like protein, MALT lymphoma-associated translocation, MLT1, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Paracaspase
- 分子量
- 93 kDa
- 基因ID
- 10892, 601217
- UniProt
- Q9UDY8
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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