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VRK1 抗体 (AA 257-396)

VRK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6150147
发货至: 中国
  • 抗原 See all VRK1 抗体
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    抗原表位
    • 15
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 257-396
    适用
    • 42
    • 11
    • 4
    宿主
    • 35
    • 7
    克隆类型
    • 37
    • 5
    多克隆
    标记
    • 23
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VRK1 antibody is un-conjugated
    应用范围
    • 40
    • 15
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    GHLPWEDNLK DPKYVRDSKI RYRENIASLM DKCFPEKNKP GEIAKYMETV KLLDYTEKPL YENLRDILLQ GLKAIGSKDD GKLDLSVVEN GGLKAKTITK KRKKEIEESK EPGVEDTEWS NTQTEEAIQT RSRTRKRVQK
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 257-396 of human VRK1 (NP_003375.1).
    亚型
    IgG
    Top Product
    Discover our top product VRK1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    VRK1 (Vaccinia Related Kinase 1 (VRK1))
    别名
    VRK1 (VRK1 产品)
    别名
    vrk1 antibody, MGC64390 antibody, MGC75762 antibody, VRK1 antibody, PCH1 antibody, PCH1A antibody, 51PK antibody, wu:fe16f06 antibody, zgc:56266 antibody, vaccinia related kinase 1 L homeolog antibody, vaccinia related kinase 1 antibody, Serine/threonine-protein kinase VRK1 antibody, vrk1.L antibody, vrk1 antibody, VRK1 antibody, vrk-1 antibody, Vrk1 antibody
    背景
    This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.,VRK1,PCH1,PCH1A,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,VRK1
    分子量
    45 kDa
    基因ID
    7443
    UniProt
    Q99986
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