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- 抗原 See all UQCRFS1 抗体
- UQCRFS1 (Ubiquinol-Cytochrome C Reductase, Rieske Iron-Sulfur Polypeptide 1 (UQCRFS1))
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抗原表位
- AA 79-274
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UQCRFS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- SHTDIKVPDF SEYRRLEVLD STKSSRESSE ARKGFSYLVT GVTTVGVAYA AKNAVTQFVS SMSASADVLA LAKIEIKLSD IPEGKNMAFK WRGKPLFVRH RTQKEIEQEA AVELSQLRDP QHDLDRVKKP EWVILIGVCT HLGCVPIANA GDFGGYYCPC HGSHYDASGR IRLGPAPLNL EVPTYEFTSD DMVIVG
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 79-274 of human UQCRFS1 (NP_005994.2).
- 亚型
- IgG
- Top Product
- Discover our top product UQCRFS1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).
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Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).
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- 抗原
- UQCRFS1 (Ubiquinol-Cytochrome C Reductase, Rieske Iron-Sulfur Polypeptide 1 (UQCRFS1))
- 别名
- UQCRFS1 (UQCRFS1 产品)
- 别名
- uqcrfs1 antibody, MGC53134 antibody, rip1 antibody, ris1 antibody, risp antibody, uqcr5 antibody, fb78f10 antibody, wu:fb05d11 antibody, wu:fb78f10 antibody, wu:fj05e12 antibody, zgc:73109 antibody, zgc:85614 antibody, GLEAN_00043 antibody, RIP1 antibody, RIS1 antibody, RISP antibody, UQCR5 antibody, 4430402G14Rik antibody, AI875505 antibody, LRRGT00195 antibody, UQCRFSL1 antibody, ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 S homeolog antibody, ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 antibody, cytochrome b-c1 complex subunit Rieske, mitochondrial antibody, iron-sulfur protein 1 antibody, uqcrfs1.S antibody, uqcrfs1 antibody, LOC661125 antibody, LOC705178 antibody, UQCRFS1 antibody, Uqcrfs1 antibody, LOC100227575 antibody, isp1 antibody
- 背景
- [Cytochrome b-c1 complex subunit Rieske, mitochondrial]: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII, ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII and cytochrome c oxidase (complex IV, CIV, that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. The Rieske protein is a catalytic core subunit containing a [2Fe-2S] iron-sulfur cluster. It cycles between 2 conformational states during catalysis to transfer electrons from the quinol bound in the Q(0 site in cytochrome b to cytochrome c1 (By similarity. Incorporation of UQCRFS1 is the penultimate step in complex III assembly.,UQCRFS1,RIP1,RIS1,RISP,UQCR5,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,UQCRFS1
- 分子量
- 29 kDa
- 基因ID
- 7386
- UniProt
- P47985
- 途径
- Proton Transport
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