STAT3 抗体 (AA 640-770)
(2 references)-
- 抗原 See all STAT3 抗体
- STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
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抗原表位
- AA 640-770
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STAT3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- YTKQQLNNMS FAEIIMGYKI MDATNILVSP LVYLYPDIPK EEAFGKYCRP ESQEHPEADP GSAAPYLKTK FICVTPTTCS NTIDLPMSPR TLDSLMQFGN NGEGAEPSAG GQFESLTFDM ELTSECATSP M
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 640-770 of human STAT3 (NP_644805.1).
- 亚型
- IgG
- Top Product
- Discover our top product STAT3 Primary Antibody
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anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (C-Term) antibody
KO Validated STAT3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (C-Term) antibodySTAT3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pSer727) antibodySTAT3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pTyr705) antibodySTAT3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 233-330) antibodySTAT3 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pSer727) antibodySTAT3 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS, IF (cc) 宿主: 兔 Monoclonal 4G1 unconjugated
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 670-769) antibodySTAT3 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4D6 unconjugated
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (C-Term) antibodyVerified STAT3 适用: 人, 小鼠 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pTyr705) antibodySTAT3 适用: 人, 小鼠, 大鼠, 兔, Pig, 小鸡 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pSer727) antibodySTAT3 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IP, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity." in: The Journal of clinical investigation, Vol. 126, Issue 9, pp. 3192-206, (2017) (PubMed).
: "MicroRNA-30c-5p ameliorates hypoxia-reoxygenation-induced tubular epithelial cell injury via HIF1α stabilization by targeting SOCS3." in: Oncotarget, Vol. 8, Issue 54, pp. 92801-92814, (2017) (PubMed).
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: "Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity." in: The Journal of clinical investigation, Vol. 126, Issue 9, pp. 3192-206, (2017) (PubMed).
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- 抗原
- STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
- 别名
- STAT3 (STAT3 产品)
- 别名
- 1110034C02Rik antibody, AW109958 antibody, Aprf antibody, APRF antibody, HIES antibody, Xstat3 antibody, aprf antibody, hies antibody, stat3 antibody, wu:fc15d02 antibody, wu:fl59g06 antibody, z-Stat3 antibody, signal transducer and activator of transcription 3 antibody, signal transduction and activation of transcription 3 antibody, signal transducer and activator of transcription 3, gene 1 L homeolog antibody, signal transducer and activator of transcription 3 (acute-phase response factor) antibody, STAT3 antibody, stat3 antibody, Stat3 antibody, stat3.1.L antibody
- 背景
- The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,ADMIO,ADMIO1,APRF,HIES,STAT3,Stat3,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Microtubules,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Stem Cells,Embryonic Stem Cells,Cardiovascular,Heart,Cardiogenesis,Hypertrophy,STAT3
- 分子量
- 83 kDa/87 kDa/88 kDa
- 基因ID
- 6774
- UniProt
- P40763
- 途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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