MTR4 抗体 (AA 1-304)
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- 抗原 See all MTR4 (SKIV2L2) 抗体
- MTR4 (SKIV2L2) (Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2))
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抗原表位
- AA 1-304
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MTR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 序列
- MADAFGDELF SVFEGDSTTA AGTKKDKEKD KGKWKGPPGS ADKAGKRFDG KLQSESTNNG KNKRDVDFEG TDEPIFGKKP RIEESITEDL SLADLMPRVK VQSVETVEGC THEVALPAEE DYLPLKPRVG KAAKEYPFIL DAFQREAIQC VDNNQSVLVS AHTSAGKTVC AEYAIALALR EKQRVIFTSP IKALSNQKYR EMYEEFQDVG LMTGDVTINP TASCLVMTTE ILRSMLYRGS EVMREVAWVI FDEIHYMRDS ERGVVWEETI ILLPDNVHYV FLSATIPNAR QFAEWICHLH KQPC
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-304 of human SKIV2L2 (NP_056175.3).
- 亚型
- IgG
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anti-Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2) antibody
SKIV2L2 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2) antibodySKIV2L2 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2) (Internal Region) antibodySKIV2L2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2) (AA 237-263) antibodySKIV2L2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22430 unconjugated
anti-Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2) antibodySKIV2L2 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2) (AA 35-84) antibodySKIV2L2 适用: 人, Cow, 犬, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MTR4 (SKIV2L2) (Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2))
- 别名
- SKIV2L2 (SKIV2L2 产品)
- 别名
- RGD1305984 antibody, zgc:63838 antibody, wu:fd11a05 antibody, SKIV2L2 antibody, skiv2l2 antibody, Dob1 antibody, KIAA0052 antibody, Mtr4 antibody, fSAP118 antibody, 2610528A15Rik antibody, mKIAA0052 antibody, Ski2 like RNA helicase 2 antibody, superkiller viralicidic activity 2-like 2 antibody, superkiller viralicidic activity 2-like 2 (S. cerevisiae) antibody, Skiv2l2 antibody, skiv2l2 antibody, SKIV2L2 antibody, LOC100380870 antibody
- 背景
- Catalyzes the ATP-dependent unwinding of RNA duplexes with a single-stranded 3' RNA extension. Central subunit of many protein complexes, namely TRAMP-like, nuclear exosome targeting (NEXT and poly(A tail exosome targeting (PAXT. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. PAXT directs a subset of long and polyadenylated poly(A RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor ZCCHC8, which links to RNA-binding protein adapters. Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. May be involved in pre-mRNA splicing. In the context of NEXT complex can also in vitro unwind DNA:RNA heteroduplexes with a 3' poly (A RNA tracking strand. Can promote unwinding and degradation of structured RNA substrates when associated with the nuclear exosome and its cofactors. Can displace a DNA strand while translocating on RNA to ultimately degrade the RNA within a DNA/RNA heteroduplex. Plays a role in DNA damage response.,SKIV2L2,Dob1,KIAA0052,Mtr4,fSAP118,Epigenetics & Nuclear Signaling,RNA Binding,SKIV2L2
- 分子量
- 117 kDa
- 基因ID
- 23517
- UniProt
- P42285
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