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SART1 抗体 (AA 1-255)

SART1 适用: 人 WB, IP, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6147390
发货至: 中国
  • 抗原 See all SART1 抗体
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    抗原表位
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-255
    适用
    • 32
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 29
    • 2
    • 1
    克隆类型
    • 32
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SART1 antibody is un-conjugated
    应用范围
    • 30
    • 13
    • 13
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
    序列
    MGSSKKHRGE KEAAGTTAAA GTGGATEQPP RHREHKKHKH RSGGSGGSGG ERRKRSRERG GERGSGRRGA EAEARSSTHG RERSQAEPSE RRVKREKRDD GYEAAASSKT SSGDASSLSI EETNKLRAKL GLKPLEVNAI KKEAGTKEEP VTADVINPMA LRQREELREK LAAAKEKRLL NQKLGKIKTL GEDDPWLDDT AAWIERSRQL QKEKDLAEKR AKLLEEMDQE FGVSTLVEEE FGQRRQDLYS ARDLQ
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human SART1 (NP_005137.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:20 - 1:50
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    别名
    SART1 (SART1 产品)
    别名
    Dmel\\CG6686 antibody, SART1 antibody, MGC53679 antibody, MGC132129 antibody, zgc:91927 antibody, Ara1 antibody, HOMS1 antibody, SART1259 antibody, SNRNP110 antibody, Snu66 antibody, U5-110K antibody, CG6686 gene product from transcript CG6686-RB antibody, SART1, U4/U6.U5 tri-snRNP-associated protein 1 S homeolog antibody, SART1, U4/U6.U5 tri-snRNP-associated protein 1 antibody, squamous-cell carcinoma T-cell-recognized antigen antibody, squamous cell carcinoma antigen recognized by T cells 1 antibody, CG6686 antibody, sart1.S antibody, sart1 antibody, SART1 antibody, Sart1 antibody
    背景
    This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.,SART1,Ara1,HOMS1,SART1259,SNRNP110,Snu66,HAF,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell differentiation,SART1
    分子量
    90 kDa
    基因ID
    9092
    UniProt
    O43290
    途径
    Ribonucleoprotein Complex Subunit Organization
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