RELB 抗体 (AA 380-579)
-
- 抗原 See all RELB 抗体
- RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))
-
抗原表位
- AA 380-579
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RELB antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- FLQRLTDGVC SEPLPFTYLP RDHDSYGVDK KRKRGMPDVL GELNSSDPHG IESKRRKKKP AILDHFLPNH GSGPFLPPSA LLPDPDFFSG TVSLPGLEPP GGPDLLDDGF AYDPTAPTLF TMLDLLPPAP PHASAVVCSG GAGAVVGETP GPEPLTLDSY QAPGPGDGGT ASLVGSNMFP NHYREAAFGG GLLSPGPEAT
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 380-579 of human RELB (NP_006500.2).
- 亚型
- IgG
- Top Product
- Discover our top product RELB Primary Antibody
-
-
- 应用备注
- WB,1:500 - 1:2000
- 说明
-
HIGH QUALITY
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))
- 别名
- RELB (RELB 产品)
- 别名
- shep antibody, I-REL antibody, IREL antibody, REL-B antibody, XRelB antibody, relb-A antibody, GC-rich antibody, avian reticuloendotheliosis viral (v-rel) oncogene related B antibody, RELB proto-oncogene, NF-kB subunit antibody, v-rel avian reticuloendotheliosis viral oncogene homolog B S homeolog antibody, Relb antibody, RELB antibody, relb.S antibody
- 背景
- NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. RELB neither associates with DNA nor with RELA/p65 or REL. Stimulates promoter activity in the presence of NFKB2/p49. Increased repression of the heterodimer is seen in the presence of NFKB2/p52. Is required for both T and B lymphocyte maturation and function.,RELB,I-REL,IREL,REL-B,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,RELB
- 分子量
- 62 kDa
- 基因ID
- 5971
- UniProt
- Q01201
- 途径
- NF-kappaB Signaling, RTK signaling
-