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RELB 抗体 (AA 380-579)

RELB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6146865
发货至: 中国
  • 抗原 See all RELB 抗体
    RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))
    抗原表位
    • 16
    • 15
    • 12
    • 10
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 380-579
    适用
    • 109
    • 71
    • 34
    • 12
    • 12
    • 8
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    宿主
    • 108
    • 5
    克隆类型
    • 94
    • 19
    多克隆
    标记
    • 62
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This RELB antibody is un-conjugated
    应用范围
    • 86
    • 27
    • 27
    • 24
    • 21
    • 19
    • 12
    • 10
    • 7
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    FLQRLTDGVC SEPLPFTYLP RDHDSYGVDK KRKRGMPDVL GELNSSDPHG IESKRRKKKP AILDHFLPNH GSGPFLPPSA LLPDPDFFSG TVSLPGLEPP GGPDLLDDGF AYDPTAPTLF TMLDLLPPAP PHASAVVCSG GAGAVVGETP GPEPLTLDSY QAPGPGDGGT ASLVGSNMFP NHYREAAFGG GLLSPGPEAT
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 380-579 of human RELB (NP_006500.2).
    亚型
    IgG
    Top Product
    Discover our top product RELB Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))
    别名
    RELB (RELB 产品)
    别名
    shep antibody, I-REL antibody, IREL antibody, REL-B antibody, XRelB antibody, relb-A antibody, GC-rich antibody, avian reticuloendotheliosis viral (v-rel) oncogene related B antibody, RELB proto-oncogene, NF-kB subunit antibody, v-rel avian reticuloendotheliosis viral oncogene homolog B S homeolog antibody, Relb antibody, RELB antibody, relb.S antibody
    背景
    NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. RELB neither associates with DNA nor with RELA/p65 or REL. Stimulates promoter activity in the presence of NFKB2/p49. Increased repression of the heterodimer is seen in the presence of NFKB2/p52. Is required for both T and B lymphocyte maturation and function.,RELB,I-REL,IREL,REL-B,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,RELB
    分子量
    62 kDa
    基因ID
    5971
    UniProt
    Q01201
    途径
    NF-kappaB Signaling, RTK signaling
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