电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PTPN13 抗体 (AA 250-500)

PTPN13 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6146442
发货至: 中国
  • 抗原 See all PTPN13 抗体
    PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))
    抗原表位
    • 16
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 250-500
    适用
    • 45
    • 11
    • 3
    宿主
    • 45
    • 1
    • 1
    克隆类型
    • 40
    • 7
    多克隆
    标记
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTPN13 antibody is un-conjugated
    应用范围
    • 14
    • 13
    • 13
    • 11
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
    序列
    QDENYFKDIL SDNSGREDSE NTFSPYQFKT SGPEKKPIPG IDVLSKKKIW ASSMDLLCTA DRDFSSGETA TYRRCHPEAV TVRTSTTPRK KEARYSDGSI ALDIFGPQKM DPIYHTRELP TSSAISSALD RIRERQKKLQ VLREAMNVEE PVRRYKTYHG DVFSTSSESP SIISSESDFR QVRRSEASKR FESSSGLPGV DETLSQGQSQ RPSRQYETPF EGNLINQEIM LKRQEEELMQ LQAKMALRQS R
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human PTPN13 (NP_542416.1).
    亚型
    IgG
    Top Product
    Discover our top product PTPN13 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))
    别名
    PTPN13 (PTPN13 产品)
    别名
    FAP-1 antibody, PNP1 antibody, PTP-BAS antibody, PTP-BL antibody, PTP1E antibody, PTPL1 antibody, PTPLE antibody, hPTP1E antibody, PTPN13 antibody, AI324989 antibody, Ptpri antibody, RIP antibody, Ptp-bl antibody, ptp antibody, wu:fb50g04 antibody, zgc:162319 antibody, protein tyrosine phosphatase, non-receptor type 13 antibody, tyrosine-protein phosphatase non-receptor type 13 antibody, PTPN13 antibody, LOC100540743 antibody, ptpn13 antibody, Ptpn13 antibody
    背景
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.,PTPN13,FAP-1,PNP1,PTP-BAS,PTP-BL,PTP1E,PTPL1,PTPLE,hPTP1E,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,PTPN13
    分子量
    255 kDa/274 kDa/276 kDa/277 kDa
    基因ID
    5783
    UniProt
    Q12923
You are here:
客服