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NUDT15 抗体 (AA 1-164)

NUDT15 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6144931
发货至: 中国
  • 抗原 See all NUDT15 抗体
    NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
    抗原表位
    • 15
    • 8
    • 5
    • 1
    • 1
    AA 1-164
    适用
    • 23
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 24
    克隆类型
    • 24
    多克隆
    标记
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    This NUDT15 antibody is un-conjugated
    应用范围
    • 19
    • 16
    • 15
    • 14
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MTASAQPRGR RPGVGVGVVV TSCKHPRCVL LGKRKGSVGA GSFQLPGGHL EFGETWEECA QRETWEEAAL HLKNVHFASV VNSFIEKENY HYVTILMKGE VDVTHDSEPK NVEPEKNESW EWVPWEELPP LDQLFWGLRC LKEQGYDPFK EDLNHLVGYK GNHL
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human NUDT15 (NP_060753.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:100
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Li, Yang, Tian, Li, Cui, Chen, Deng, Chen, Hayakawa, Sekiguchi, Cai: "MutT-related proteins are novel progression and prognostic markers for colorectal cancer." in: Oncotarget, Vol. 8, Issue 62, pp. 105714-105726, (2017) (PubMed).

  • 抗原
    NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
    别名
    NUDT15 (NUDT15 产品)
    别名
    MTH2 antibody, RP11-90M2.1 antibody, 6530403O17 antibody, A730068G11Rik antibody, nudix hydrolase 15 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 15 antibody, NUDT15 antibody, Nudt15 antibody
    背景
    This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.,NUDT15,MTH2,NUDT15D,Epigenetics & Nuclear Signaling,NUDT15
    分子量
    18 kDa
    基因ID
    55270
    UniProt
    Q9NV35
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