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Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) 抗体

DUSP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6139873
发货至: 中国
  • 抗原 See all Dual Specificity Phosphatase 3 (DUSP3) 抗体
    Dual Specificity Phosphatase 3 (DUSP3)
    抗原表位
    • 15
    • 8
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-185
    适用
    • 40
    • 21
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 51
    • 7
    克隆类型
    • 51
    • 7
    多克隆
    标记
    • 26
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 40
    • 23
    • 14
    • 13
    • 13
    • 13
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MSGSFELSVQ DLNDLLSDGS GCYSLPSQPC NEVTPRIYVG NASVAQDIPK LQKLGITHVL NAAEGRSFMH VNTNANFYKD SGITYLGIKA NDTQEFNLSA YFERAADFID QALAQKNGRV LVHCREGYSR SPTLVIAYLM MRQKMDVKSA LSIVRQNREI GPNDGFLAQL CQLNDRLAKE GKLKP
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human DUSP3 (NP_004081.1).
    亚型
    IgG
    Top Product
    Discover our top product DUSP3 Primary Antibody
  • 应用备注
    WB,1:500 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Dual Specificity Phosphatase 3 (DUSP3)
    别名
    DUSP3 (DUSP3 产品)
    别名
    dusp3 antibody, si:bz18k17.3 antibody, si:rp71-18k17.3 antibody, VHR antibody, RGD1560049 antibody, 2210015O03Rik antibody, 5031436O03Rik antibody, T-DSP11 antibody, dual specificity phosphatase 3 antibody, dual specificity phosphatase 3b antibody, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) antibody, DUSP3 antibody, dusp3b antibody, Dusp3 antibody
    物质类
    Viral Protein
    背景
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.,DUSP3,VHR,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,DUSP3
    分子量
    16 kDa/20 kDa
    基因ID
    1845
    UniProt
    P51452
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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