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Caspase 4 抗体 (AA 81-266)

CASP4 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6137966
发货至: 中国
  • 抗原 See all Caspase 4 (CASP4) 抗体
    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
    抗原表位
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-266
    适用
    • 58
    • 32
    • 15
    • 14
    • 1
    小鼠
    宿主
    • 77
    • 10
    • 1
    • 1
    • 1
    克隆类型
    • 76
    • 13
    多克隆
    标记
    • 52
    • 15
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Caspase 4 antibody is un-conjugated
    应用范围
    • 73
    • 29
    • 27
    • 12
    • 9
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 81-266 of mouse Caspase-4 (P70343).
    亚型
    IgG
    Top Product
    Discover our top product CASP4 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zuo, Kong, Wang, Liu, Wang, Wan, Yan, Zhang, Tang, Zhang, Lyu, Li, Shan, Qian, Shen, Yu: "CRTH2 promotes endoplasmic reticulum stress-induced cardiomyocyte apoptosis through m-calpain." in: EMBO molecular medicine, Vol. 10, Issue 3, (2018) (PubMed).

  • 抗原
    Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
    别名
    CASP4 (CASP4 产品)
    别名
    ICE(rel)II antibody, ICEREL-II antibody, ICH-2 antibody, Mih1/TX antibody, TX antibody, Casp11 antibody, CASP13 antibody, CASP1 antibody, CASP4 antibody, Caspl antibody, ich-3 antibody, Casp4 antibody, caspase 4 antibody, caspase 4, apoptosis-related cysteine peptidase antibody, caspase-4 antibody, CASP4 antibody, Casp4 antibody, LOC100731032 antibody
    背景
    This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.,Cas, ich-, Caspa, Caspl, ich-3, CASP-4, Casp11, CASP-11,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Endocrine & Metabolism,Immunology & Inflammation,CASP4
    分子量
    13 kDa/18 kDa/30 kDa/36 kDa/43 kDa
    基因ID
    12363
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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