C8orf4 抗体 (AA 1-106)
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- 抗原 See all C8orf4 抗体
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
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抗原表位
- AA 1-106
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C8orf4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MKAKRSHQAI IMSTSLRVSP SIHGYHFDTA SRKKAVGNIF ENTDQESLER LFRNSGDKKA EERAKIIFAI DQDVEEKTRA LMALKKRTKD KLFQFLKLRK YSIKVH
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human C8orf4 (NP_064515.1).
- 亚型
- IgG
- Top Product
- Discover our top product C8orf4 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
- 别名
- C8orf4 (C8orf4 产品)
- 背景
- This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.,C8orf4,TC-1,TC1,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Stem Cells,C8orf4
- 分子量
- 12 kDa
- 基因ID
- 56892
- UniProt
- Q9NR00
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