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FE65 抗体 (AA 359-708)

APBB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6136973
发货至: 中国
  • 抗原 See all FE65 (APBB1) 抗体
    FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
    抗原表位
    • 15
    • 15
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 359-708
    适用
    • 56
    • 38
    • 27
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 58
    • 1
    • 1
    克隆类型
    • 60
    多克隆
    标记
    • 18
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This FE65 antibody is un-conjugated
    应用范围
    • 59
    • 39
    • 39
    • 14
    • 10
    • 9
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    PPRNTNPGIK CFAVRSLGWV EMTEEELAPG RSSVAVNNCI RQLSYHKNNL HDPMSGGWGE GKDLLLQLED ETLKLVEPQS QALLHAQPII SIRVWGVGRD SGRDFAYVAR DKLTQMLKCH VFRCEAPAKN IATSLHEICS KIMAERRNAR CLVNGLSLDH SKLVDVPFQV EFPAPKNELV QKFQVYYLGN VPVAKPVGVD VINGALESVL SSSSREQWTP SHVSVAPATL TILHQQTEAV LGECRVRFLS FLAVGRDVHT FAFIMAAGPA SFCCHMFWCE PNAASLSEAV QAACMLRYQK CLDARSQAST SCLPAPPAES VARRVGWTVR RGVQSLWGSL KPKRLGAHTP
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 359-708 of human APBB1 (NP_663722.1).
    亚型
    IgG
    Top Product
    Discover our top product APBB1 Primary Antibody
  • 应用备注
    WB,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
    别名
    APBB1 (APBB1 产品)
    别名
    FE65 antibody, MGC:9072 antibody, RIR antibody, apbb1 antibody, MGC80654 antibody, Fe65 antibody, Rir antibody, amyloid beta precursor protein binding family B member 1 antibody, amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog antibody, amyloid beta (A4) precursor protein-binding, family B, member 1 antibody, APBB1 antibody, apbb1.L antibody, Apbb1 antibody
    背景
    The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.,APBB1,FE65,MGC:9072,RIR,Epigenetics & Nuclear Signaling,Signal Transduction,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,APBB1
    分子量
    49 kDa/52 kDa/53 kDa/54 kDa/76 kDa/77 kDa
    基因ID
    322
    UniProt
    O00213
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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