PHAP1 抗体 (AA 1-170)
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- 抗原 See all PHAP1 (ANP32A) 抗体
- PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))
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抗原表位
- AA 1-170
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PHAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI NVGLTSIANL PKLNKLKKLE LSDNRVSGGL EVLAEKCPNL THLNLSGNKI KDLSTIEPLK KLENLKSLDL FNCEVTNLND YRENVFKLLP QLTYLDGYDR DDKEAPDSDA EGYVEGLDDE
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ANP32A (NP_006296.1).
- 亚型
- IgG
- Top Product
- Discover our top product ANP32A Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))
- 别名
- ANP32A (ANP32A 产品)
- 别名
- C15orf1 antibody, HPPCn antibody, I1PP2A antibody, LANP antibody, MAPM antibody, PHAP1 antibody, PHAPI antibody, PP32 antibody, Anp32 antibody, W91701 antibody, pp32 antibody, Anp32a antibody, CG5784 antibody, CT18148 antibody, CT42180 antibody, Dmel\\CG5784 antibody, anon-EST:fe3A2 antibody, wu:fj36e08 antibody, zgc:55516 antibody, ANP32D antibody, acidic nuclear phosphoprotein 32 family member A antibody, acidic (leucine-rich) nuclear phosphoprotein 32 family, member A antibody, CG5784 gene product from transcript CG5784-RB antibody, acidic nuclear phosphoprotein 32 family member A L homeolog antibody, ANP32A antibody, Anp32a antibody, Mapmodulin antibody, anp32a antibody, anp32a.L antibody
- 背景
- Multifunctional protein that is involved in the regulation of many processes including tumor suppression, apoptosis, cell cycle progression or transcription. Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation. In addition, plays a role in the modulation of histone acetylation and transcription as part of the INHAT (inhibitor of histone acetyltransferases complex. Inhibits the histone-acetyltranferase activity of EP300/CREBBP (CREB-binding protein and EP300/CREBBP-associated factor by histone masking. Preferentially binds to unmodified histone H3 and sterically inhibiting its acetylation and phosphorylation leading to cell growth inhibition. Participates in other biochemical processes such as regulation of mRNA nuclear-to-cytoplasmic translocation and stability by its association with ELAVL1 (Hu-antigen R. Plays a role in E4F1-mediated transcriptional repression as well as inhibition of protein phosphatase 2A.,ANP32A,C15orf1,HPPCn,I1PP2A,LANP,MAPM,PHAP1,PHAPI,PP32,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Caspases,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,ANP32A
- 分子量
- 28 kDa
- 基因ID
- 8125
- UniProt
- P39687
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