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TGF-beta 抗体

TGFb 适用: 人 WB, Neut, ELISA, Func, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal TB21 unconjugated
产品编号 ABIN604857
发货至: 中国
  • 抗原 See all TGF-beta (TGFb) 抗体
    TGF-beta (TGFb)
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TGF-beta antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Neutralization (Neut), ELISA, Functional Studies (Func), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    品牌
    IHC-plus™
    特异性
    Recognizes both human platelet-derived and recombinant TGF-beta.
    纯化方法
    Protein G purified
    免疫原
    TGF-b from human platelets.

    Type of Immunogen: Purified protein
    克隆位点
    TB21
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TGFb Primary Antibody
  • 应用备注
    Approved: ELISA, Func, IHC, IHC-Fr, IHC-P (10 μg/mL), Neut, WB

    Usage: Suitable for use in Western Blot, ELISA, Neutralization and Immunohistochemistry. Neutralization: Neutralizes TGF-beta activity in vitro in an inhibition assay of CCL/64 cell growth and the growth promoting action of TGF-beta in the NRK-49F colony forming assay. The effect of microinjection of this antibody into one blastomere of two cell stage Xenopus embryos indicated that it was able to neutralize effectively the bioactivity of TGF-beta in vivo. Immunohistochemistry (formalin-fixed, paraffin-embedded, frozen): 1:1000. Has been used to demonstrate TGF-beta in ovine ovarian tissue and human breast carcinoma. As a consequence of the intense staining of the erythrocytes it is possible to locate a single cell within the ovarian stroma making it useful in locating very fine capillary networks within tissue. Western Blot: 5-20 ng/mL will allow visualization of 100 ng/lane of TGF-beta. Recognizes the dimeric (25kD) and monomeric (12.5kD) forms of TGF-beta under both non-reducing and reducing conditions respectively.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.0.
    注意事项
    avoid freeze thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
  • Baumeier, Escher, Aleshcheva, Pietsch, Schultheiss: "Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy." in: Basic research in cardiology, Vol. 116, Issue 1, pp. 1, (2021) (PubMed).

  • 抗原
    TGF-beta (TGFb)
    别名
    TGF-beta (TGFb 产品)
    别名
    CED antibody, DPD1 antibody, LAP antibody, TGFB antibody, TGFbeta antibody, TGF-beta antibody, TGF-BETA-1 antibody, TGF-beta1 antibody, TGFbeta1 antibody, Tgfb antibody, Tgfb-1 antibody, transforming growth factor beta 1 antibody, transforming growth factor beta-1 antibody, transforming growth factor, beta 1 antibody, TGFB1 antibody, Tgfb1 antibody
    途径
    EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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