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Contactin 1 抗体 (AA 100-150)

CNTN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN571798
发货至: 中国
  • 抗原 See all Contactin 1 (CNTN1) 抗体
    Contactin 1 (CNTN1)
    抗原表位
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-150
    适用
    • 43
    • 18
    • 17
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    宿主
    • 38
    • 2
    • 2
    • 1
    克隆类型
    • 42
    • 1
    多克隆
    标记
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Contactin 1 antibody is un-conjugated
    应用范围
    • 30
    • 21
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for contactin-1.
    交叉反应
    人, 大鼠
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from AA 100-150 of human contactin 1 conjugated to an immunogenic carrier protein was used as the antigen.
    亚型
    IgG
    Top Product
    Discover our top product CNTN1 Primary Antibody
  • 应用备注
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    Contactin 1 (CNTN1)
    别名
    Contactin 1 (CNTN1 产品)
    别名
    F3 antibody, GP135 antibody, AW495098 antibody, CNTN antibody, F3cam antibody, F3/F11 antibody, cntn-A antibody, F11 antibody, CNTN1 antibody, cntn1 antibody, contactin 1 antibody, contactin 1 L homeolog antibody, contactin 1a antibody, CNTN1 antibody, Cntn1 antibody, cntn1.L antibody, cntn1a antibody
    背景
    FUNCTION: Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth. SUBUNIT: Monomer. Interacts with CNTNAP1 in cis form. Binds to the carbonic-anhydrase like domain of protein-tyrosine phosphatase zeta. Interacts with NOTCH1 and TNR. SUBCELLULAR LOCATION: Cell membrane, Lipid-anchor, GPI-anchor. MISCELLANEOUS: F3 shares with L1, N-CAM, MAG, and other cell adhesion molecules from nervous tissue the L2/HNK-1 carbohydrate epitope. TISSUE SPECIFICITY: Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle.,Contactin Family,Neural cell surface protein F3, F3cam, contactin 1, CNTN1, Glycoprotein gp135
    UniProt
    Q12860
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