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RRP8 抗体

RRP8 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5705951
发货至: 中国
  • 抗原 See all RRP8 抗体
    RRP8 (Ribosomal RNA Processing 8 (RRP8))
    适用
    • 23
    • 11
    • 10
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 21
    • 2
    克隆类型
    • 23
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRP8 antibody is un-conjugated
    应用范围
    • 14
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    免疫原
    ribosomal RNA processing 8, methyltransferase, homolog (yeast)
    亚型
    IgG
    Top Product
    Discover our top product RRP8 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    human brain tissue were subjected to SDS PAGE followed by western blot with FNab07501(RRP8 antibody) at dilution of 1:1500

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    RRP8 (Ribosomal RNA Processing 8 (RRP8))
    别名
    RRP8 (RRP8 产品)
    别名
    KIAA0409 antibody, 1500003O22Rik antibody, 2900001K19Rik antibody, AW538116 antibody, RGD1308302 antibody, ribosomal RNA processing 8 antibody, ribosomal RNA processing 8, methyltransferase, homolog (yeast) antibody, RRP8 antibody, Rrp8 antibody
    背景
    Synonyms:KIAA0409, NML Background:Essential component of the eNoSC(energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9'(H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
    基因ID
    23378
    UniProt
    O43159
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