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NMRAL1 抗体

NMRAL1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5704605
发货至: 中国
  • 抗原 See all NMRAL1 抗体
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    适用
    • 12
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 11
    • 2
    克隆类型
    • 13
    多克隆
    标记
    • 9
    • 2
    • 1
    • 1
    This NMRAL1 antibody is un-conjugated
    应用范围
    • 8
    • 7
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    免疫原
    NmrA-like family domain containing 1
    亚型
    IgG
    Top Product
    Discover our top product NMRAL1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05769(NMRAL1 antibody) at dilution of 1:500

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    别名
    NMRAL1 (NMRAL1 产品)
    别名
    HSCARG antibody, SDR48A1 antibody, 1110025F24Rik antibody, AI256624 antibody, RGD1311451 antibody, NmrA like redox sensor 1 antibody, NmrA-like family domain containing 1 antibody, NMRAL1 antibody, Nmral1 antibody
    背景
    Synonyms:HSCARG Background:Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase(ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.
    分子量
    33 kDa
    基因ID
    57407
    UniProt
    Q9HBL8
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