DCLRE1B 抗体
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- 抗原 See all DCLRE1B 抗体
- DCLRE1B (DNA Cross-Link Repair 1B (DCLRE1B))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DCLRE1B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 免疫原
- DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae)
- 亚型
- IgG
- Top Product
- Discover our top product DCLRE1B Primary Antibody
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anti-DNA Cross-Link Repair 1B (DCLRE1B) (AA 208-236) antibody
DCLRE1B 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB26835 unconjugated
anti-DNA Cross-Link Repair 1B (DCLRE1B) (C-Term) antibodyDCLRE1B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-DNA Cross-Link Repair 1B (DCLRE1B) (AA 345-493) antibodyDCLRE1B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA Cross-Link Repair 1B (DCLRE1B) antibodyDCLRE1B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Cross-Link Repair 1B (DCLRE1B) (AA 323-532) antibodyDCLRE1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- DCLRE1B (DNA Cross-Link Repair 1B (DCLRE1B))
- 别名
- DCLRE1B (DCLRE1B 产品)
- 别名
- APOLLO antibody, SNM1B antibody, SNMIB antibody, im:6894074 antibody, zgc:154089 antibody, AI452214 antibody, Apollo antibody, mSNM1B antibody, DNA cross-link repair 1B antibody, DCLRE1B antibody, Dclre1b antibody, dclre1b antibody
- 背景
- Synonyms:SNM1B Background:5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining(NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop(T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase(TOP1, TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology. Also involved in response to DNA damage: plays a role in response to DNA interstrand cross-links(ICLs) by facilitating double-strand break formation. In case of spindle stress, involved in prophase checkpoint.
- 分子量
- 60 kDa
- 基因ID
- 64858
- UniProt
- Q9H816
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