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BRD8 抗体

BRD8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN5702375
发货至: 中国
  • 抗原 See all BRD8 抗体
    BRD8 (Bromodomain Containing 8 (BRD8))
    适用
    • 25
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    宿主
    • 24
    • 2
    小鼠
    克隆类型
    • 24
    • 2
    单克隆
    标记
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BRD8 antibody is un-conjugated
    应用范围
    • 12
    • 8
    • 7
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    免疫原
    bromodomain containing 8
    亚型
    IgG1
    Top Product
    Discover our top product BRD8 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    BRD8 (Bromodomain Containing 8 (BRD8))
    别名
    BRD8 (BRD8 产品)
    别名
    SMAP antibody, SMAP2 antibody, p120 antibody, 2610007E11Rik antibody, 4432404P07Rik antibody, bromodomain containing 8 antibody, BRD8 antibody, Brd8 antibody
    背景
    Synonyms:SMAP, SMAP2 Background:May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors(NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase(HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
    分子量
    120 kDa
    基因ID
    10902
    UniProt
    Q9H0E9
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