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VPS4B 抗体

vps4b 适用: 人, 小鼠, 大鼠 WB, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5701702
发货至: 中国
  • 抗原 See all VPS4B (vps4b) 抗体
    VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
    适用
    • 43
    • 17
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 42
    • 1
    克隆类型
    • 43
    多克隆
    标记
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VPS4B antibody is un-conjugated
    应用范围
    • 38
    • 22
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
    免疫原
    vacuolar protein sorting 4 homolog B (S. cerevisiae)
    亚型
    IgG
    Top Product
    Discover our top product vps4b Primary Antibody
  • 应用备注
    WB :1:500-1:5000,IP:1:500-1:5000,IF:1:10-1:100
    说明

    Y79 cells were subjected to SDS PAGE followed by western blot with FNab09446(VPS4B antibody) at dilution of 1:500

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze / thaw cycles.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
    别名
    VPS4B (vps4b 产品)
    别名
    zgc:63682 antibody, vps4a antibody, SKD1 antibody, SKD1B antibody, VPS4-2 antibody, 8030489C12Rik antibody, Skd1 antibody, vacuolar protein sorting 4 homolog B antibody, vacuolar protein sorting 4 homolog B S homeolog antibody, vacuolar protein sorting 4b homolog B (S. cerevisiae) antibody, vacuolar protein sorting 4 homolog B (S. cerevisiae) antibody, vacuolar protein sorting 4B antibody, Vps4b antibody, vps4b.S antibody, vps4b antibody, VPS4B antibody
    背景
    Synonyms:MIG1, Protein SKD1, SKD1, VPS4 2, VPS42, VPS4B Background:Involved in late steps of the endosomal multivesicular bodies(MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding(HIV-1 and other lentiviruses). VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan(PubMed:22660413).
    分子量
    49kDa
    基因ID
    9525
    UniProt
    O75351
    途径
    Microtubule Dynamics, CXCR4-mediated Signaling Events
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