DYNLT1 抗体
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- 抗原 See all DYNLT1 抗体
- DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DYNLT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 免疫原
- dynein, light chain, Tctex-type 1
- 亚型
- IgG
- Top Product
- Discover our top product DYNLT1 Primary Antibody
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anti-Dynein, Light Chain, Tctex-Type 1 (DYNLT1) (AA 1-80) antibody
DYNLT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynein, Light Chain, Tctex-Type 1 (DYNLT1) (N-Term) antibodyDYNLT1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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human brain tissue were subjected to SDS PAGE followed by western blot with FNab02590(DYNLT1 antibody) at dilution of 1:500
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))
- 别名
- DYNLT1 (DYNLT1 产品)
- 别名
- cw-1 antibody, tctel1 antibody, dynlt1a antibody, tctex-1 antibody, MGC85297 antibody, tctex1 antibody, Ci-LC3 antibody, CW-1 antibody, TCTEL1 antibody, AGS2 antibody, Tctex1 antibody, dynein light chain Tctex-type 1 L homeolog antibody, dynein light chain Tctex-type 1 antibody, dynein, light chain, Tctex-type 1 antibody, dynlt1.L antibody, DYNLT1 antibody, dynlt1 antibody, Dynlt1 antibody
- 背景
- Synonyms:TCTEL1, TCTEX-1, TCTEX1 Background:Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site. May also be a accessory component of axonemal dynein. Plays a role in neuronal morphogenesis, the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling, the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis, inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation(By similarity).
- 分子量
- 12 kDa
- 基因ID
- 6993
- UniProt
- P63172
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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