DACH1 抗体
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- 抗原 See all DACH1 抗体
- DACH1 (Dachshund 1 (DACH1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DACH1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 免疫原
- dachshund homolog 1 (Drosophila)
- 亚型
- IgG
- Top Product
- Discover our top product DACH1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab02230( DACH1 Antibody) at dilution of 1:600
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- DACH1 (Dachshund 1 (DACH1))
- 别名
- DACH1 (DACH1 产品)
- 别名
- DACH antibody, AI182278 antibody, Dac antibody, Dach antibody, E130112M23Rik antibody, dach antibody, dachshund family transcription factor 1 antibody, dachshund 1 (Drosophila) antibody, dachshund family transcription factor 1 S homeolog antibody, dachshund homolog 1 antibody, DACH1 antibody, Dach1 antibody, dach1.S antibody, dach1 antibody, LOC100550020 antibody
- 背景
- Synonyms:DACH Background:Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter(By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain(By similarity).
- 分子量
- 97-100 kDa
- 基因ID
- 1602
- UniProt
- Q9UI36
- 途径
- Feeding Behaviour
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