UPF3A 抗体
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- 抗原 See all UPF3A 抗体
- UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UPF3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 免疫原
- UPF3 regulator of nonsense transcripts homolog A (yeast)
- 亚型
- IgG
- Top Product
- Discover our top product UPF3A Primary Antibody
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- 应用备注
- WB : 1:500-1:5000,IHC:1:20-1:200,IF:1:20-1:200
- 说明
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human testis tissue were subjected to SDS PAGE followed by western blot with FNab09271(UPF3A antibody) at dilution of 1:500
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
- 别名
- UPF3A (UPF3A 产品)
- 别名
- 2600001C03Rik antibody, 4930546M19Rik antibody, RENT3A antibody, UPF3 antibody, UPF3A antibody, HUPF3A antibody, si:dkey-21o13.6 antibody, UPF3 regulator of nonsense transcripts homolog A (yeast) antibody, UPF3A, regulator of nonsense mediated mRNA decay antibody, Upf3a antibody, UPF3A antibody, upf3a antibody
- 背景
- Synonyms:HUpf3, HUPF3A, RENT3A, UPF3, UPF3A Background:Involved in nonsense-mediated decay(NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex(EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex(including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. However, UPF3A is shown to be only marginally active in NMD as compared to UPF3B. Binds spliced mRNA upstream of exon-exon junctions. In vitro, weakly stimulates translation.
- 分子量
- 123kDa
- 基因ID
- 65110
- UniProt
- Q9H1J1
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