SART3 抗体
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- 抗原 See all SART3 抗体
- SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SART3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 免疫原
- squamous cell carcinoma antigen recognized by T cells 3
- 亚型
- IgG
- Top Product
- Discover our top product SART3 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab07612(SART3 antibody) at dilution of 1:1000
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze / thaw cycles.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
- 别名
- SART3 (SART3 产品)
- 别名
- SART3 antibody, DKFZp469J2418 antibody, si:ch211-191d15.4 antibody, wu:fc51h03 antibody, DSAP1 antibody, P100 antibody, RP11-13G14 antibody, TIP110 antibody, p110 antibody, p110(nrb) antibody, AU045857 antibody, mKIAA0156 antibody, squamous cell carcinoma antigen recognized by T-cells 3 antibody, squamous cell carcinoma antigen recognized by T-cells 3 L homeolog antibody, squamous cell carcinoma antigen recognized by T cells 3 antibody, SART3 antibody, sart3 antibody, sart3.L antibody, Sart3 antibody
- 背景
- Synonyms:DSAP1, hSART 3, KIAA0156, P100, p110, p110(nrb), RP11 13G14, SART 3, SART3, TIP110, Background:U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation(PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites(PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly(PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair(PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC(By similarity).
- 基因ID
- 9733
- UniProt
- Q15020
- 途径
- Ribonucleoprotein Complex Subunit Organization
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