SCRIB 抗体 (AA 172-409) (DyLight 488)
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- 抗原 See all SCRIB 抗体
- SCRIB (Scribbled Homolog (SCRIB))
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抗原表位
- AA 172-409
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SCRIB antibody is conjugated to DyLight 488
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应用范围
- Flow Cytometry (FACS)
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG Polyclonal Anti-Human SCRIBBLE Antibody DyLight® 488 Conjugated, Flow Validated.
- 免疫原
- E. coli-derived human SCRIBBLE recombinant protein (Position: F172-K409).
- Top Product
- Discover our top product SCRIB Primary Antibody
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anti-Scribbled Homolog (SCRIB) antibody
SCRIB 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Scribbled Homolog (SCRIB) antibodySCRIB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Scribbled Homolog (SCRIB) (AA 382-410), (N-Term) antibodySCRIB 适用: 人 WB 宿主: 兔 Polyclonal RB39490 unconjugated
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- 应用备注
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Application Details: Flow Cytometry, 1-3 μg/1x106 cells
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- At 2-8°C for one year. Protect from light. Do not freeze.
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- 抗原
- SCRIB (Scribbled Homolog (SCRIB))
- 别名
- SCRIB (SCRIB 产品)
- 背景
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Synonyms: Protein scribble homolog, Scribble, hScrib, Protein LAP4, SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Tissue Specificity: Expressed in kidney, skeletal muscles, liver, lung, breast, intestine, placenta and skin mainly in epithelial cells (at protein level).
Background: SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. In Drosophila melanogaster, SCRIB is involved in synaptic function, neuroblast differentiation, and epithelial polarization. Mechanistically, the human homolog is a scaffold protein linked to cellular differentiation centered on the regulation of epithelial as well as neuronal morphogenesis. Deficiency in SCRIB impairs many aspects of cell polarity and cell movement. SCRIB is also likely involved in establishing apical-basal polarity as well as progression from the G1 phase to S phase in the cell cycle as a result of its relationship with cell proliferation and exocytosis.
- UniProt
- Q14160
- 途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
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