ADO 抗体 (AA 49-261) (DyLight 488)
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- 抗原 See all ADO 抗体
- ADO (2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO))
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抗原表位
- AA 49-261
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADO antibody is conjugated to DyLight 488
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应用范围
- Flow Cytometry (FACS)
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG Polyclonal Anti-Human ADO Antibody DyLight® 488 Conjugated, Flow Validated.
- 免疫原
- E. coli-derived human ADO recombinant protein (Position: E49-E261). Human ADO shares 90.1% amino acid (aa) sequence identity with mouse ADO.
- Top Product
- Discover our top product ADO Primary Antibody
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anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) antibody
ADO 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) antibodyADO 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) (AA 137-270) antibodyADO 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) (AA 206-233), (C-Term) antibodyADO 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB30095 unconjugated
anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) (AA 206-233), (C-Term) antibodyADO 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Details: Flow Cytometry, 1-3 μg/1x106 cells
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- At 2-8°C for one year. Protect from light. Do not freeze.
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- 抗原
- ADO (2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO))
- 别名
- ADO (ADO 产品)
- 别名
- C10orf22 antibody, Gm237 antibody, RGD1308233 antibody, wu:fc32g01 antibody, wu:fc52c12 antibody, zgc:101580 antibody, 2-aminoethanethiol dioxygenase antibody, 2-aminoethanethiol (cysteamine) dioxygenase antibody, 2-aminoethanethiol (cysteamine) dioxygenase a antibody, ADO antibody, Ado antibody, LOC100351598 antibody, adoa antibody
- 背景
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Synonyms: 2-aminoethanethiol dioxygenase, Cysteamine dioxygenase, ADO, C10orf22
Background: Human thiol dioxygenases include cysteine dioxygenase (CDO) and cysteamine (2-aminoethanethiol) dioxygenase (ADO). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine. It is demonstrated that mouse Ado has strong and specific dioxygenase activity in vitro towards cysteamine but not cysteine. Recombinant Ado was shown to bind iron. Overexpression of Ado in HepG2/C3A cells increased the production of hypotaurine from cysteamine. Similar results were found with human ADO. When endogenous expression of ADO was reduced by RNA-mediated interference, hypotaurine production decreased. It is also noted that the demonstration of high levels of ADO in brain challenges the previous assumption that most of the taurine in the brain is a consequence of CDO activity.
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