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ASXL1 抗体

ASXL1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5693162
发货至: 中国
  • 抗原 See all ASXL1 抗体
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    适用
    人, 小鼠, 大鼠
    宿主
    • 29
    • 2
    克隆类型
    • 29
    • 2
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASXL1 antibody is un-conjugated
    应用范围
    • 22
    • 16
    • 14
    • 14
    • 14
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB)
    品牌
    Picoband™
    序列
    KKERTWAEAA RLVLENYSDA PMTPKQILQV IEAE
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for ASXL1 detection. Tested with WB in Human,Mouse,Rat.
    免疫原
    A synthetic peptide corresponding to a sequence of human ASXL1 (KKERTWAEAARLVLENYSDAPMTPKQILQVIEAE).
    Top Product
    Discover our top product ASXL1 Primary Antibody
  • 应用备注

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Application Details: Western blot, 0.1-0.5 μg/mL

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    别名
    ASXL1 (ASXL1 产品)
    别名
    asxl1 antibody, MGC83850 antibody, mKIAA0978 antibody, BOPS antibody, MDS antibody, additional sex combs like 1, transcriptional regulator L homeolog antibody, additional sex combs like 1, transcriptional regulator antibody, additional sex combs like 1 antibody, asxl1.L antibody, ASXL1 antibody, asxl1 antibody, Asxl1 antibody
    背景

    Synonyms: Putative Polycomb group protein ASXL1, Additional sex combs-like protein 1, ASXL1, KIAA0978

    Tissue Specificity: Widely expressed at low level. Expressed in heart, brain, skeletal muscle, placenta, pancreas, spleen, prostate, small intestine, colon, peripheral blood, leukocytes, bone marrow and fetal liver. Highly expressed in testes.

    Background: Putative Polycomb group protein ASXL1 is a protein that in humans is encoded by the ASXL1 gene. This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.

    途径
    Retinoic Acid Receptor Signaling Pathway
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