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Galectin 10 抗体 (AA 2-142)

CLC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5693147
发货至: 中国
  • 抗原 See all Galectin 10 (CLC) 抗体
    Galectin 10 (CLC) (Charcot-Leyden Crystal Protein (CLC))
    抗原表位
    • 9
    • 9
    • 8
    • 7
    • 7
    • 1
    • 1
    • 1
    AA 2-142
    适用
    • 39
    • 2
    • 1
    宿主
    • 35
    • 5
    克隆类型
    • 35
    • 5
    多克隆
    标记
    • 18
    • 7
    • 5
    • 4
    • 3
    • 3
    This Galectin 10 antibody is un-conjugated
    应用范围
    • 32
    • 24
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    品牌
    Picoband™
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Galectin 10 detection. Tested with WB, Direct ELISA in Human.
    免疫原
    E. coli-derived human Galectin 10 recombinant protein (Position: S2-R142).
    Top Product
    Discover our top product CLC Primary Antibody
  • 应用备注

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Application Details: Western blot, 0.1-0.5 μg/mL
    Direct ELISA, 0.1-0.5 μg/mL

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    Galectin 10 (CLC) (Charcot-Leyden Crystal Protein (CLC))
    别名
    CLC (CLC 产品)
    别名
    GAL10 antibody, Gal-10 antibody, LGALS10 antibody, LGALS10A antibody, LPPL_HUMAN antibody, Clcp antibody, gal-10 antibody, Bsf3 antibody, CLC antibody, GAL 10 antibody, Gal-8 antibody, Gal8 antibody, Charcot-Leyden crystal galectin antibody, Charcot-Leyden crystal protein antibody, cardiotrophin-like cytokine factor 1 antibody, avian beta-defensin 10 antibody, CLC antibody, Clc antibody, Clcf1 antibody, AvBD10 antibody
    背景

    Synonyms: Galectin-10, Gal-10, Charcot-Leyden crystal protein, CLC, Eosinophil lysophospholipase, Lysolecithin acylhydrolase, CLC, LGALS10, LGALS10A

    Tissue Specificity: Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and to the number of eosinophils found in the duodenal lesion (at protein level). Found in sputum of patients with eosinophilic inflammatory diseases such as asthma (at protein level).

    Background: Eosinophil lysophospholipase is an enzyme that in humans is encoded by the CLC gene. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.

    UniProt
    Q05315
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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