BAMBI
适用: 人, 大鼠, 小鼠, Pig
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 680
应用备注
BAMBI antibody can be used for detection of BAMBI by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
BAMBI antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
BAMBI antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原
BAMBI
(BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))
NMA antibody, bambi antibody, nma antibody, BAMBI antibody, Zfnma antibody, cb998 antibody, fc44c12 antibody, id:ibd5020 antibody, wu:fc44c12 antibody, wu:fe01e03 antibody, 2610003H06Rik antibody, bambi-A antibody, zgc:91871 antibody, BMP and activin membrane bound inhibitor antibody, BMP and activin membrane-bound inhibitor homolog antibody, BMP and activin membrane-bound inhibitor antibody, BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a antibody, BMP and activin membrane-bound inhibitor L homeolog antibody, BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b antibody, BAMBI antibody, bambi antibody, bambia antibody, Bambi antibody, LOC724378 antibody, LOC100647353 antibody, bambi.L antibody, bambib antibody
背景
BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development (1). BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4 (2,3). BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues (4). BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines (5).