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ABL1/2 抗体 (AA 391-395, AA 427-231)
ABL1/ABL2
适用: 人, 小鼠
WB
宿主: 兔
Polyclonal
unconjugated
ABL1/2抗体详情
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抗原
See all ABL1/2 (ABL1/ABL2) 抗体
ABL1/2 (ABL1/ABL2)
(Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))
抗原表位
All epitopes for ABL1/2 抗体
AA 391-395, AA 427-231
适用
All reactivities for ABL1/2 抗体
人, 小鼠
宿主
All hosts for ABL1/2 抗体
兔
克隆类型
All clonalities for ABL1/2 抗体
多克隆
标记
All conjugates for ABL1/2 抗体
This ABL1/2 antibody is un-conjugated
应用范围
All applications for ABL1/2 抗体
Western Blotting (WB)
特异性
This antibody detects endogenous levels of total ABL1/2 protein.
纯化方法
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
免疫原
ABL1/2 (Ab-393/429) antibody was raised against a peptide sequence around aa.391~395/427~431 (D-T-Y-T-A) derived from ABL1/2 .
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Alternatives
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使用细节
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应用备注
Western Blot: 1:500~1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store antibody at -20°C for up to one year.
ABL1/2目标详情
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抗原
ABL1/2 (ABL1/ABL2)
(Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))
别名
ABL1 / 2 (ABL1/ABL2 产品 )
别名
CABL antibody, ABLL antibody, cb272 antibody, ABL proto-oncogene 2, non-receptor tyrosine kinase antibody, c-abl oncogene 2, non-receptor tyrosine kinase antibody, ABL2 antibody, abl2 antibody
背景
Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
分子量
135, 210 kDa
基因ID
25, 27
NCBI登录号
NP_005148 , NP_001129472
UniProt
P00519 , P42684
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