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COMMD1 抗体 (AA 1-190)

COMMD1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2A12 unconjugated
产品编号 ABIN566862
发货至: 中国
  • 抗原 See all COMMD1 抗体
    COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))
    抗原表位
    • 15
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-190
    适用
    • 40
    • 22
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 45
    • 10
    小鼠
    克隆类型
    • 48
    • 7
    单克隆
    标记
    • 25
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This COMMD1 antibody is un-conjugated
    应用范围
    • 35
    • 20
    • 13
    • 13
    • 10
    • 8
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    原理
    Mouse monoclonal antibody raised against a full length recombinant COMMD1.
    序列
    MAAGELEGGK PLSGLLNALA QDTFHGYPGI TEELLRSQLY PEVPPEEFRP FLAKMRGILK SIASADMDFN QLEAFLTAQT KKQGGITSDQ AAVISKFWKS HKTKIRESLM NQSRWNSGLR GLSWRVDGKS QSRHSAQIHT PVAIIELELG KYGQESEFLC LEFDEVKVNQ ILKTLSEVEE SISTLISQPN
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    COMMD1 (AAH22046.1, 1 a.a. ~ 190 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    2A12
    亚型
    IgG2a
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • OHara, Simpson, Morin, Loveridge, Williams, Novo, Stark: "p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-?B subunit." in: Journal of cell science, Vol. 127, Issue Pt 17, pp. 3659-65, (2014) (PubMed).

    Schilling, Bayer, Li, Molls, Vaupel, Multhoff: "Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1?." in: PLoS ONE, Vol. 7, Issue 2, pp. e31110, (2012) (PubMed).

    Drévillon, Tanguy, Hinzpeter, Arous, de Becdelièvre, Aissat, Tarze, Goossens, Fanen: "COMMD1-mediated ubiquitination regulates CFTR trafficking." in: PLoS ONE, Vol. 6, Issue 3, pp. e18334, (2011) (PubMed).

    Vonk, Wijmenga, Berger, van de Sluis, Klomp: "Cu,Zn superoxide dismutase maturation and activity are regulated by COMMD1." in: The Journal of biological chemistry, Vol. 285, Issue 37, pp. 28991-9000, (2010) (PubMed).

    Huang, Wu, Li: "Tumor suppressor ARF promotes non-classic proteasome-independent polyubiquitination of COMMD1." in: The Journal of biological chemistry, Vol. 283, Issue 17, pp. 11453-60, (2008) (PubMed).

    Burkhead, Morgan, Shinde, Haddock, Lutsenko: "COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with phosphatidylinositol 4,5-bisphosphate." in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 696-707, (2008) (PubMed).

    Weiss, Lozoya, Tuma, Gotthardt, Reichert, Ehehalt, Stremmel, Füllekrug: "Copper-induced translocation of the Wilson disease protein ATP7B independent of Murr1/COMMD1 and Rab7." in: The American journal of pathology, Vol. 173, Issue 6, pp. 1783-94, (2008) (PubMed).

    Maine, Mao, Komarck, Burstein: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." in: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).

    de Bie, van de Sluis, Burstein, van de Berghe, Muller, Berger, Gitlin, Wijmenga, Klomp: "Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B." in: Gastroenterology, Vol. 133, Issue 4, pp. 1316-26, (2007) (PubMed).

  • 抗原
    COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))
    别名
    COMMD1 (COMMD1 产品)
    别名
    C2orf5 antibody, MURR1 antibody, murr1 antibody, commd1 antibody, si:ch211-213b8.2 antibody, DDBDRAFT_0184206 antibody, DDBDRAFT_0266452 antibody, DDB_0184206 antibody, DDB_0266452 antibody, COMMD1 antibody, MGC114682 antibody, AI256843 antibody, Murr1 antibody, U2/Mu antibody, copper metabolism domain containing 1 antibody, copper metabolism (Murr1) domain containing 1 antibody, COMM domain-containing protein 1 antibody, copper metabolism domain containing 1 L homeolog antibody, COMM domain containing 1 antibody, COMMD1 antibody, commd1 antibody, comd1 antibody, Commd1 antibody, commd1.L antibody
    背景
    Full Gene Name: copper metabolism (Murr1) domain containing 1
    Synonyms: C2orf5,MGC27155,MURR1
    基因ID
    150684
    途径
    Transition Metal Ion Homeostasis
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