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Recombinant CD33 (Gemtuzumab Biosimilar) 抗体

适用: 人 FACS, IF 宿主: 兔 Monoclonal HP67-6 unconjugated Recombinant Antibody
产品编号 ABIN5668211
发货至: 中国
  • 抗原 See all CD33 (Gemtuzumab Biosimilar) products
    CD33 (Gemtuzumab Biosimilar)
    抗体类型
    Recombinant Antibody
    适用
    宿主
    • 2
    • 1
    • 1
    • 1
    克隆类型
    • 5
    单克隆
    标记
    • 5
    This CD33 (Gemtuzumab Biosimilar) antibody is un-conjugated
    应用范围
    • 5
    • 3
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    Recognises human CD33.
    产品特性

    OriginalSpeciesName: Human

    OriginalFormat: IgG4

    纯化方法
    Purified antibody.
    纯度
    > 98 % as determined by SDS-PAGE
    内毒素水平
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    免疫原
    Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
    克隆位点
    HP67-6
    亚型
    IgG kappa
  • 应用备注
    A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    CD33 (Gemtuzumab Biosimilar)
    Abstract
    CD33 (Gemtuzumab Biosimilar) 产品
    别名
    SIGLEC-3 antibody, SIGLEC3 antibody, p67 antibody, CD33 molecule antibody, CD33 antibody
    物质类
    Biosimilar
    背景
    Siglec-3
    UniProt
    P20138
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