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Recombinant TNF alpha (Adalimumab Biosimilar) 抗体

适用: 人 ELISA, IF, IHC, BR 宿主: 兔 Monoclonal D2E7 unconjugated Recombinant Antibody
产品编号 ABIN5668146
发货至: 中国
  • 抗原 See all TNF alpha (Adalimumab Biosimilar) products
    TNF alpha (Adalimumab Biosimilar)
    抗体类型
    Recombinant Antibody
    适用
    宿主
    • 2
    • 2
    • 1
    • 1
    克隆类型
    • 6
    单克隆
    标记
    • 6
    This TNF alpha (Adalimumab Biosimilar) antibody is un-conjugated
    应用范围
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Blocking Reagent (BR)
    特异性
    Binds to soluble TNF-alpha, but not to lymphotoxin (TNF beta).
    产品特性

    OriginalSpeciesName: Human

    OriginalFormat: IgG1

    纯化方法
    Purified antibody.
    纯度
    > 98 % as determined by SDS-PAGE
    内毒素水平
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    免疫原
    This antibody was generated by affinity maturation from the 2SD4 scFv, which in turn was selected on human TNF alpha by guided phage-display technology, using the murine anti-hTNF alpha antibody Mab32 as a template (c.f. also US Patent 6090382).
    克隆位点
    D2E7
    亚型
    IgG kappa
  • 应用备注
    Adalimumab binds specifically to TNF and neutralizes the biological function of TNF by blocking its interaction with the p55 and p75 cell surface TNF receptors.
    说明

    NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    TNF alpha (Adalimumab Biosimilar)
    Abstract
    TNF alpha (Adalimumab Biosimilar) 产品
    别名
    DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, tumor necrosis factor antibody, TNF antibody
    物质类
    Biosimilar
    背景
    Tumor necrosis factor alpha
    UniProt
    P01375
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