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ADAM17 抗体 (C-Term)

ADAM17 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5663782
发货至: 中国
  • 抗原 See all ADAM17 抗体
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    抗原表位
    • 16
    • 13
    • 13
    • 8
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 115
    • 54
    • 52
    • 4
    • 4
    • 4
    • 1
    • 1
    宿主
    • 100
    • 13
    • 2
    • 1
    • 1
    克隆类型
    • 92
    • 25
    多克隆
    标记
    • 54
    • 11
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    This ADAM17 antibody is un-conjugated
    应用范围
    • 87
    • 53
    • 40
    • 15
    • 14
    • 14
    • 12
    • 11
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    KQYESLSLFH PSNVEMLSSM DSASVRIIKP FPAPQTPGRL QPAPVIPSAP AAPKLDHQRM DTIQEDPSTD SHMDEDGFEK DPFPNSSTAA KSFEDLTDHP VTRSEKAASF KLQRQNRVDS KETEC
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human ADAM17 (NP_003174.3).
    亚型
    IgG
    Top Product
    Discover our top product ADAM17 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    别名
    ADAM17 (ADAM17 产品)
    别名
    ADAM18 antibody, CD156B antibody, CSVP antibody, NISBD antibody, TACE antibody, CD156b antibody, Tace antibody, adam17 antibody, si:dkey-81b15.2 antibody, adam18 antibody, cd156b antibody, csvp antibody, tace antibody, fc20b01 antibody, wu:fc20b01 antibody, zgc:63886 antibody, ADAM metallopeptidase domain 17 antibody, a disintegrin and metallopeptidase domain 17 antibody, ADAM metallopeptidase domain 17b antibody, ADAM metallopeptidase domain 17 L homeolog antibody, ADAM metallopeptidase domain 17a antibody, ADAM17 antibody, Adam17 antibody, adam17b antibody, adam17.L antibody, adam17a antibody
    背景
    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha, in which soluble tumor necrosis factor-alpha is released from the membrane-bound precursor. This protease also functions in the processing of numerous other substrates, including cell adhesion proteins, cytokine and growth factor receptors and epidermal growth factor (EGF) receptor ligands. The encoded protein also plays a prominent role in the activation of the Notch signaling pathway. Elevated expression of this gene has been observed in specific cell types derived from psoriasis, rheumatoid arthritis, multiple sclerosis and Crohn's disease patients, suggesting that the encoded protein may play a role in autoimmune disease.,ADAM17,ADAM18,CD156B,CSVP,NISBD,NISBD1,TACE,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Extracellular Matrix,ADAM Protein Family,Ubiquitin,Notch Signaling Pathway,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Stem Cells,ADAM17
    分子量
    78 kDa/93 kDa
    基因ID
    6868
    UniProt
    P78536
    途径
    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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