电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

SLC5A8 抗体 (AA 579-609)

SLC5A8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647944
发货至: 中国
  • 抗原 See all SLC5A8 抗体
    SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
    抗原表位
    • 14
    • 12
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 579-609
    适用
    • 34
    • 28
    • 24
    • 5
    • 5
    • 5
    • 1
    宿主
    • 45
    克隆类型
    • 45
    多克隆
    标记
    • 12
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC5A8 antibody is un-conjugated
    应用范围
    • 40
    • 21
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 579-609 from the human protein was used as the immunogen for the SLC5A8 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SLC5A8 Primary Antibody
  • 应用备注
    Western blot: 1:500-1000
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the SLC5A8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
    别名
    SLC5A8 / Sodium-coupled monocarboxylate transporter 1 (SLC5A8 产品)
    别名
    Ait antibody, SMCT antibody, SMCT1 antibody, AIT antibody, RGD1564146 antibody, solute carrier family 5 (iodide transporter), member 8 antibody, solute carrier family 5 member 8 antibody, Slc5a8 antibody, SLC5A8 antibody
    背景
    Solute carrier family 5 member 8 acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D- hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D- lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.
    基因ID
    160728
    UniProt
    Q8N695
You are here:
客服