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alpha Actinin 4 抗体

ACTN4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5647002
发货至: 中国
  • 抗原 See all alpha Actinin 4 (ACTN4) 抗体
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    适用
    • 86
    • 44
    • 41
    • 8
    • 4
    • 4
    • 4
    • 3
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    • 3
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    • 2
    • 1
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 79
    • 7
    克隆类型
    • 67
    • 18
    多克隆
    标记
    • 54
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    This alpha Actinin 4 antibody is un-conjugated
    应用范围
    • 67
    • 30
    • 26
    • 17
    • 16
    • 15
    • 12
    • 12
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids E561-V661 from the human protein were used as the immunogen for the ACTN4 antibody.
    亚型
    IgG
    Top Product
    Discover our top product ACTN4 Primary Antibody
  • 应用备注
    Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    Prior to reconstitution, store at 4°C. After reconstitution, the ACTN4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    别名
    ACTN4 / Alpha Actinin 4 (ACTN4 产品)
    别名
    fsgs antibody, fsgs1 antibody, C77391 antibody, ACTININ-4 antibody, FSGS antibody, FSGS1 antibody, wu:fb53f05 antibody, zgc:63508 antibody, actinin alpha 4 antibody, actinin, alpha 4 antibody, actinin alpha 4 S homeolog antibody, actn4 antibody, ACTN4 antibody, Actn4 antibody, actn4.S antibody
    背景
    Alpha-actinin-4 is a protein that in humans is encoded by the ACTN4 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This ACTN4 gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
    UniProt
    O43707
    途径
    Proton Transport
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