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MFN2 抗体 (AA 661-757)

Name: MFN2 抗体 (AA 661-757)
SKU: ABIN564263
Availability: OutOfStock

MFN2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4H8 unconjugated

MFN2 monoclonal antibody (M03), clone 4H8 Western Blot analysis of MFN2 expression in HeLa .

Immunoperoxidase of monoclonal antibody to MFN2 on formalin-fixed paraffin-embedded human heart.

ISt

Western blot analysis of MFN2 over-expressed 293 cell line, cotransfected with MFN2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1).

Detection limit for recombinant GST tagged MFN2 is approximately 1ng/ml as a capture antibody.

ELISA

Western Blot analysis of MFN2 expression in transfected 293T cell line by MFN2 monoclonal antibody (M03), clone 4H8.

MFN2 monoclonal antibody (M03), clone 4H8.

Western Blot detection against Immunogen (36.

7 images

(8 references)

产品编号 ABIN564263

发货至: 中国

Datasheet as PDF

抗原 See all MFN2 抗体

MFN2 (Mitofusin 2 (MFN2))
抗原表位
29

16

7

6

5

3

2

2

2

1

1

1

1

1

1

1

1
AA 661-757
适用
79

52

36

20

4

4

4

4

3

2

2

2

2

1

1

1

1
人
宿主
67

31

2
小鼠
Compatible Secondaries
克隆类型
68

32
单克隆
标记
35

8

7

7

6

4

4

4

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This MFN2 antibody is un-conjugated
应用范围
89

51

33

23

22

16

15

13

13

8

3

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

原理

Mouse monoclonal antibody raised against a partial recombinant MFN2.

序列

FKRQFVEHAS EKLQLVISYT GSNCSHQVQQ ELSGTFAHLC QQVDVTRENL EQEIAAMNKK IEVLDSLQSK AKLLRNKAGW LDSELNMFTH QYLQPSR

交叉反应

人, 大鼠

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

MFN2 (NP_055689, 661 a.a. ~ 757 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆位点

4H8

亚型

IgG2a
anti-Mitofusin 2 (MFN2) (AA 1-120) antibody
MFN2 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 500-600) antibody
MFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 687-757) antibody
MFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 447-476) antibody
MFN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (HRP)
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 HRP

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (FITC)
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 FITC

anti-Mitofusin 2 (MFN2) (N-Term) antibody
MFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Alkaline Phosphatase (AP))
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 Alkaline Phosphatase (AP)

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Biotin)
MFN2 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S153-5 Biotin

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Chen, Chen, Wang, Tan, Zhu, Li, Han, Chen, Gao, Liu, Chen: "Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy." in: Autophagy, Vol. 12, Issue 4, pp. 689-702, (2016) (PubMed).

Esteves, G-Fernandes, Santos, Januário, Cardoso: "The Upshot of LRRK2 Inhibition to Parkinson's Disease Paradigm." in: Molecular neurobiology, (2015) (PubMed).

Fiuza-Luces, Delmiro, Soares-Miranda, González-Murillo, Martínez-Palacios, Ramírez, Lucia, Morán: "Exercise training can induce cardiac autophagy at end-stage chronic conditions: insights from a graft-versus-host-disease mouse model." in: Brain, behavior, and immunity, Vol. 39, pp. 56-60, (2014) (PubMed).

Lally, Herbst, Matravadia, Maher, Perry, Ventura-Clapier, Holloway: "Over-expressing mitofusin-2 in healthy mature mammalian skeletal muscle does not alter mitochondrial bioenergetics." in: PLoS ONE, Vol. 8, Issue 1, pp. e55660, (2013) (PubMed).

Russell, Lamon, Boon, Wada, Güller, Brown, Chibalin, Zierath, Snow, Stepto, Wadley, Akimoto: "Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training." in: The Journal of physiology, Vol. 591, Issue Pt 18, pp. 4637-53, (2013) (PubMed).

Cosson, Marchetti, Ravazzola, Orci: "Mitofusin-2 independent juxtaposition of endoplasmic reticulum and mitochondria: an ultrastructural study." in: PLoS ONE, Vol. 7, Issue 9, pp. e46293, (2012) (PubMed).

Morán, Rivera, Sánchez-Aragó, Blázquez, Merinero, Ugalde, Arenas, Cuezva, Martín: "Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts." in: Biochimica et biophysica acta, Vol. 1802, Issue 5, pp. 443-53, (2010) (PubMed).

Holloway, Perry, Thrush, Heigenhauser, Dyck, Bonen, Spriet: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).
抗原

MFN2 (Mitofusin 2 (MFN2))

别名

MFN2 (MFN2 产品)

别名

CG3869 antibody, Dmel\\CG3869 antibody, MARF antibody, Marf-1 antibody, Mfn antibody, anon-WO0125274.3 antibody, dMFN antibody, dMfn antibody, dmfn antibody, marf antibody, mfn antibody, mfn2 antibody, MFN2 antibody, hsg antibody, cmt2a antibody, cprp1 antibody, cmt2a2 antibody, CMT2A antibody, CMT2A2 antibody, CPRP1 antibody, HSG antibody, D630023P19Rik antibody, Fzo antibody, mg:cb01g09 antibody, si:dkeyp-104h9.2 antibody, wu:fb79a11 antibody, mitofusin 2 antibody, Mitochondrial assembly regulatory factor antibody, mitofusin-2 antibody, mitofusin 2 L homeolog antibody, MFN2 antibody, Marf antibody, mfn2 antibody, LOC100186475 antibody, Mfn2 antibody, mfn2.L antibody

背景

Full Gene Name: mitofusin 2
Synonyms: CMT2A,CMT2A2,CPRP1,HSG,KIAA0214,MARF

基因ID

9927

NCBI登录号

NM_014874

途径

Skeletal Muscle Fiber Development