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RAB27A 抗体 (AA 122-221)

RAB27A 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1G7 unconjugated
产品编号 ABIN562560
发货至: 中国
  • 抗原 See all RAB27A 抗体
    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
    抗原表位
    • 13
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 122-221
    适用
    • 50
    • 23
    • 21
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 42
    • 5
    • 3
    • 2
    小鼠
    克隆类型
    • 47
    • 5
    单克隆
    标记
    • 30
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAB27A antibody is un-conjugated
    应用范围
    • 38
    • 27
    • 10
    • 9
    • 5
    • 4
    • 4
    • 4
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)
    原理
    Mouse monoclonal antibody raised against a partial recombinant RAB27A.
    序列
    YCENPDIVLC GNKSDLEDQR VVKEEEAIAL AEKYGIPYFE TSAANGTNIS QAIEMLLDLI MKRMERCVDK SWIPEGVVRS NGHASTDQLS EEKEKGACGC
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    RAB27A (NP_004571, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    1G7
    亚型
    IgG1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Felicetti, De Feo, Coscia, Puglisi, Pedini, Pasquini, Bellenghi, Errico, Pagani, Carè: "Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma." in: Journal of translational medicine, Vol. 14, pp. 56, (2016) (PubMed).

    Hannafon, Carpenter, Berry, Janknecht, Dooley, Ding: "Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)." in: Molecular cancer, Vol. 14, pp. 133, (2015) (PubMed).

    Cetica, Hackmann, Grieve, Sieni, Ciambotti, Coniglio, Pende, Gilmour, Romagnoli, Griffiths, Aricò: "Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding." in: The Journal of allergy and clinical immunology, (2014) (PubMed).

    Kimura, Yamaoka, Taniguchi, Okamoto, Takei, Ando, Iwamatsu, Watanabe, Kaibuchi, Ishizaki, Niki: "Activated Cdc42-bound IQGAP1 determines the cellular endocytic site." in: Molecular and cellular biology, Vol. 33, Issue 24, pp. 4834-43, (2013) (PubMed).

    Peinado, Ale?kovi?, Lavotshkin, Matei, Costa-Silva, Moreno-Bueno, Hergueta-Redondo, Williams, García-Santos, Ghajar, Nitadori-Hoshino, Hoffman, Badal, Garcia, Callahan, Yuan, Martins, Skog, Kaplan et al.: "Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. ..." in: Nature medicine, Vol. 18, Issue 6, pp. 883-91, (2012) (PubMed).

    Sanchez-Ruiz, Valitutti, Dupre: "Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes." in: PLoS ONE, Vol. 6, Issue 11, pp. e27057, (2011) (PubMed).

    Neumüller, Hoffmeister, Babica, Prelle, Gegenbauer, Smolenski: "Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets." in: Blood, Vol. 114, Issue 7, pp. 1396-404, (2009) (PubMed).

    Kimura, Kaneko, Yamada, Ishihara, Senda, Iwamatsu, Niki: "The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines." in: Journal of cell science, Vol. 121, Issue Pt 18, pp. 3092-8, (2008) (PubMed).

  • 抗原
    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))
    别名
    RAB27A (RAB27A 产品)
    别名
    MGC80943 antibody, RAB27A antibody, gs2 antibody, ram antibody, rab27 antibody, MGC89827 antibody, hst18676 antibody, zgc:114135 antibody, GS2 antibody, HsT18676 antibody, RAB27 antibody, RAM antibody, 2210402C08Rik antibody, 2410003M20Rik antibody, 4933437C11Rik antibody, ash antibody, RAB27A, member RAS oncogene family L homeolog antibody, RAB27A, member RAS oncogene family antibody, RAB27A, member RAS oncogene family S homeolog antibody, rab27a.L antibody, RAB27A antibody, rab27a antibody, rab27a.S antibody, Rab27a antibody
    背景
    Full Gene Name: RAB27A, member RAS oncogene family
    Synonyms: GS2,HsT18676,MGC117246,RAB27,RAM
    基因ID
    5873
    NCBI登录号
    NM_004580
    途径
    Peptide Hormone Metabolism
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