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HMGB1 抗体 (AA 1-215)

HMGB1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D5 unconjugated
产品编号 ABIN561281
发货至: 中国
  • 抗原 See all HMGB1 抗体
    HMGB1 (High Mobility Group Box 1 (HMGB1))
    抗原表位
    • 20
    • 16
    • 16
    • 11
    • 10
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-215
    适用
    • 156
    • 88
    • 87
    • 14
    • 12
    • 12
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    宿主
    • 137
    • 29
    • 2
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 127
    • 45
    单克隆
    标记
    • 89
    • 17
    • 17
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HMGB1 antibody is un-conjugated
    应用范围
    • 145
    • 63
    • 47
    • 46
    • 32
    • 30
    • 27
    • 26
    • 21
    • 10
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Mouse monoclonal antibody raised against a full length recombinant HMGB1.
    序列
    MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEE EDEEDEDEEE DDDDE
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    HMGB1 (AAH03378.1, 1 a.a. ~ 215 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    1D5
    亚型
    IgG2a
    Top Product
    Discover our top product HMGB1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Ko, Hsu, Hsieh, Lien, Lee, Kou: "High expression of high-mobility group box 1 in the blood and lungs is associated with the development of chronic obstructive pulmonary disease in smokers." in: Respirology (Carlton, Vic.), Vol. 19, Issue 2, pp. 253-61, (2014) (PubMed).

    Demoulin, Herfs, Somja, Roncarati, Delvenne, Hubert: "HMGB1 secretion during cervical carcinogenesis promotes the acquisition of a tolerogenic functionality by plasmacytoid dendritic cells." in: International journal of cancer. Journal international du cancer, (2014) (PubMed).

    Hirano, Yoshioka, Yunoue, Fujio, Yonezawa, Niiro, Habu, Oyoshi, Sugata, Kamezawa, Arimura, Hanaya, Tokimura, Tokudome, Arita: "TLR4, IL-6, IL-18, MyD88 and HMGB1 are highly expressed in intracranial inflammatory lesions and the IgG4/IgG ratio correlates with TLR4 and IL-6." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 32, Issue 6, pp. 628-37, (2012) (PubMed).

    Krüger, Krick, Dhillon, Lerner, Ames, Bromberg, Lin, Walsh, Vella, Fischereder, Krämer, Colvin, Heeger, Murphy, Schröppel: "Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 9, pp. 3390-5, (2009) (PubMed).

    Kijanka, Hector, Kay, Murray, Cummins, Murphy, MacCraith, Prehn, Kenny: "Human IgG antibody profiles differentiate between symptomatic patients with and without colorectal cancer." in: Gut, Vol. 59, Issue 1, pp. 69-78, (2009) (PubMed).

  • 抗原
    HMGB1 (High Mobility Group Box 1 (HMGB1))
    别名
    HMGB1 (HMGB1 产品)
    别名
    HMG1 antibody, HMG3 antibody, SBP-1 antibody, DEF antibody, HMG-1 antibody, Hmg1 antibody, amphoterin antibody, p30 antibody, hmgb1 antibody, ik:tdsubc_1a5 antibody, wu:fb23c02 antibody, xx:tdsubc_1a5 antibody, zgc:56110 antibody, zgc:77104 antibody, hmg-1 antibody, hmg3 antibody, sbp-1 antibody, hmg1 antibody, HMGB1 antibody, Ac2-008 antibody, high mobility group box 1 antibody, high-mobility group box 1 antibody, high mobility group box 1a antibody, high mobility group box 1 L homeolog antibody, high mobility group protein B1 antibody, HMGB1 antibody, Hmgb1 antibody, hmgb1 antibody, hmgb1a antibody, hmgb1.L antibody, LOC100359149 antibody
    背景
    Full Gene Name: high-mobility group box 1
    Synonyms: DKFZp686A04236,HMG1,HMG3,SBP-1
    基因ID
    3146
    途径
    p53 Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
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