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Desmoplakin 抗体 (C-Term, pSer2849)

DSP 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5596788
发货至: 中国
  • 抗原 See all Desmoplakin (DSP) 抗体
    Desmoplakin (DSP)
    抗原表位
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, pSer2849
    适用
    • 32
    • 16
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 27
    • 4
    • 2
    克隆类型
    • 29
    • 4
    多克隆
    标记
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmoplakin antibody is un-conjugated
    应用范围
    • 14
    • 11
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    交叉反应 (详细)
    A BLAST analysis was used to suggest cross-reactivity with mouse and human based on 100% sequence homology. Cross-reactivity with Desmoplakin pS2849 from other sources has not been determined.
    纯化方法
    Anti-Desmoplakin pS2849 was affinity purified from monospecific antiserum by immunoaffinity chromatography and is directed against the phosphorylated form of the S2849 human residue.
    免疫原

    Immunogen: Anti-Desmoplakin pS2849 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide near the C-terminus of human Desmoplakin protein.

    Immunogen Type: Peptide

    亚型
    IgG
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    Discover our top product DSP Primary Antibody
  • 应用备注

    Application Note: Anti-Desmoplakin pS2849 antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~331 kDa corresponding to the appropriate cell lysate or extract.

    Western Blot Dilution: 1 μg/mL

    ELISA Dilution: 1: 10,000

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.67 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 30 % Glycerol

    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    Desmoplakin (DSP)
    别名
    Desmoplakin (DSP 产品)
    别名
    DP antibody, DPI antibody, DPII antibody, DSP antibody, dpi antibody, dpii antibody, 2300002E22Rik antibody, 5730453H04Rik antibody, AA407887 antibody, AA407888 antibody, AW109828 antibody, im:6911953 antibody, sb:cb570 antibody, wu:fc17a08 antibody, wu:fk73d01 antibody, desmoplakin antibody, Desmoplakin antibody, ORF113 antibody, desmoplakin a antibody, ORF112 DESMOPLAKIN antibody, orf102 antibody, orf91; similar to Cydia pomonella granulovirus orf112 antibody, ORF62 antibody, ORF-66 antibody, ORF57 antibody, agip105 antibody, similar to XcORF133; similar to HaGV desmoplakin antibody, desmoplakin L homeolog antibody, ORF96 antibody, DSP antibody, PhopGV104 antibody, ORF-59 desmoplakin antibody, desmop antibody, Dsp antibody, dsp antibody, desmoplakin antibody, dspa antibody, orf112 desmoplakin antibody, ClgVgp102 antibody, COGV_gp091 antibody, APNV_p087 antibody, CBNV_gp066 antibody, EONV_gp057 antibody, OLNV_gp066 antibody, AgipMNPV_gp105 antibody, HaMNV_gp106 antibody, EupsNPV_gp065 antibody, PsunGV_gp139 antibody, dsp.L antibody, ClanGV_gp096 antibody
    背景

    Synonyms: 250/210 kDa paraneoplastic pemphigus antigen, DSP, DPI, DPII

    Background: Desmoplakin pS2849 is high molecular weight protein of desmosomes. It is a member of the plakin or cytolinker family and is involved in the organization of the desmosomal cadherin-plakoglobin complexes into plasma membrane domains in the anchoring of intermediate filaments to the desmosomes. The phosphorylation theoretically affects its association with epidermal, simple cytokeratins and VIM intermediate filaments. Defects in DSP are the cause of keratosis palmoplantaris striata II, Carvajal syndrome, and arrhythmogenic right ventricular cardiomyopathy 8. Anti-Desmoplakin pS2849 Antibody is ideal for researchers interested in Cell Structure research.

    Gene Name: DSP

    途径
    Cell-Cell Junction Organization
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